Dr Goh Bey Hing

Contact Details

BSc. (Hons), PhD Biochemistry (UM)
Lecturer – Pharmacy


Office: Building 2, Level 5, Room 45
Tel: +603 5514 4487
Fax: +603 5514 6364
Email: goh.bey.hing@monash.edu

Dr. Goh Bey Hing joined Monash University Malaysia as a lecturer in March 2013. He obtained his BSc. (Hons.) and Ph.D. in Biochemistry from University of Malaya. He has great experience and immense knowledge in molecular and cellular biology studies, especially in deciphering the apoptotic modulatory effects of natural products on human cancer cell lines. Apart from that, he also engaged himself with the molecular studies of neuropharmacological activities of natural products. His research projects are mainly emphasizing on the importance of fundamental understanding of the molecular pathways modulation by bioactive compounds, as it is essential to the development of new therapeutic strategies for different chronic diseases. His current research interests reside in exploring pharmacological potentials of medicinal plants and microbes for the benefit of mankind.

(A) Teaching

SUBJECT CODESUBJECT
PAC2161Cell function, communication and pathology
PAC1111Introduction to physiology
MED1011Medicine 1
MED2031Medicine 3

(B) Areas of Expertise

1Drug discovery                                                 
2Molecular Oncology
3Ethnopharmacology
4Neuroscience                    
5Molecular Therapeutics

Academic Qualifications

Doctor of Philosophy (PhD)
InstitutionUniversity Malaya
Year Awarded2012
 
Bachelor of Science (Hons.)
InstitutionUniversity Malaya                        
Year Awarded2008

(A) BOOKS

Tan Loh, T.H., Lee, L.H. & Goh, B.H. (2016). Bioprospecting of anti-Vibrio activity of Streptomyces species. ISBN:978-3-659-85939-7.

(B) BOOK CHAPTERS

Ser, H. L., Palanisamy, U. D., Yin, W. F., Malek, A. S., Chan, K. G., Goh, B. H. & Lee, L. H. (2016). Presence of antioxidative agent, Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro- in newly isolated Streptomyces mangrovisoli sp. nov. In Sheng Qin, Wen-Jun Li, Syed G. Dastager and Wael N. Hozzein (Eds.), Actinobacteria in special and extreme habitats: diversity, function roles and environmental adaptations, (pp. 170-180). (DOI 10.3389/978-2-88945-013-8). ISBN 978-2-88945-013-8
Tan, L. T. H, Ser, H. L., Yin, W. F., Chan, K. G., Lee, L. H., & Goh, B. H. (2016). Investigation of antioxidative and anticancer potentials of Streptomyces sp. MUM256 isolated from Malaysia mangrove soil. In Sheng Qin, Wen-Jun Li, Syed G. Dastager and Wael N. Hozzein (Eds.), Actinobacteria in special and extreme habitats: diversity, function roles and environmental adaptations, (pp. 181-192).  (DOI 10.3389/978-2-88945-013-8). ISBN 978-2-88945-013-8 

(C)  SCHOLARLY JOURNALS

Tang, C., Hoo, C.X., Tan Loh, T.H., Priyia, P., Tahir, M.K., Lee, L.H., Goh, B.H.*, & Chan, K.G.* (2016). Golden needle mushroom: A culinary medicine with evidenced-based biological activities and health promoting properties. Frontiers in Pharmacology. (doi: 10.3389/fphar.2016.00474 ) (ISI Cited, IF: 4.418, Tier 1)
Khan, T. M.*, Wu, D. B. C., Goh, B. H., Lee, L. H., Alhafez, A. A., & Sulaiman, S. A. S. (2016). An Observational Longitudinal Study Investigating the Effectiveness of 75 mg Pregabalin Post-Hemodialysis among Uremic Pruritus Patients, 6, Scientific Reports. (doi: 10.1038/srep36555) (ISI Cited, IF: 5.578, Tier 1)
Tan, H.L., Chan, K.G., Pusparajah, P., Duangjai, A., Saokaew, S., Khan, T.M., Lee, L.H.*& Goh, B.H.* (2016). Rhizoma coptidis: A potential cardiovascular protective agent. 7, Frontiers in Pharmacology. (doi: 10.3389/fphar.2016.00362 ) (ISI Cited, IF: 4.418, Q1)
Vengadesh Letchumanan, H.L.S., Tan, W.S., Ab Mutalib, N.S., Goh, B.H., Chan, K.G.* & Lee, L.H.* (2016). Genome sequence of Vibrio parahaemolyticus VP152 strain isolated from Penaeus indicus in Malaysia. 7, Frontiers in Microbiology. (doi: 10.3389/fmicb.2016.01410) (ISI Cited, IF: 4.165, Q1)
Azman, A.S., Othman, I., Fang, C.M., Chan, K.G., Goh, B.H.* & Lee, L.H.* (2016). Antibacterial, anticancer and neuroprotective activities of rare actinobacteria from mangro ve forest soils. Indian Journal of Microbiology. (doi: 10.1007/s12088-016-0627-z ) (ISI Cited, IF: 1.143, Q4)
Ser, H.L., Tan, W.S., Ab Mutalib, N.S., Yin, W.F., Chan, K.G., Goh, B.H.* & Lee, L.H.*, 2016. Draft Genome Sequence of Mangrove-Derived Streptomyces sp. MUSC 125 with Antioxidant Potential. 7, Frontiers in Microbiology. (doi:10.3389/fmicb.2016.01470 ) (ISI Cited, IF: 4.165, Q1)
Vengadesh Letchumanan, H.L.S., Chan, K.G., Goh, B.H.* and Lee, L.H.* (2016). Genome Sequence of Vibrio parahaemolyticus VP103 Strain Isolated from Shrimp in Malaysia. 7, Frontiers in Microbiology. (ISI Cited, IF: 4.165, Q1)
Tan, H.L., Chan, K.G., Pusparajah, P., Saokaew, S., Duangjai, A., Lee, L.H.* & Goh, B.H.* (2016). Anti-cancer Properties of the Naturally Occurring Aphrodisiacs: Icariin and Its Derivatives. Frontiers in Pharmacology. (doi: 10.3389/fphar.2016.00191 ) (ISI Cited, IF: 4.418, Q1)
Letchumanan, V., Chan, K. G., Pusparajah, P., Saokaew, S., Duangjai, A., Goh, B. H.*, Syakima, N.S.A. & Lee, L. H.* (2016). Insights into bacteriophage application in controlling Vibrio species. Frontiers in Microbiology, 7, 1114. (ISI Cited, IF: 4.165, Q1)
Hoo, J.Y., Yatinesh, K., Shaikh, M.F., Hue, S.M. & Goh, B.H.* (2016). Zebrafish: a versatile animal model for fertility research. BioMed Research International. (ISI Cited, IF: 2.134, Q3)
Ser, H. L., Tan, L. T. H., Palanisamy, U. D., Abd Malek, S. N., Yin, W. F., Chan, K. G., Goh, B.H.* & Lee, L. H.* (2016). Streptomyces antioxidans sp. nov., a novel mangrove soil actinobacterium with antioxidative and neuroprotective potentials. Frontiers in Microbiology, 7, 899. (ISI Cited, IF: 4.165, Q1)
Sayyad, M., Ning, T., Kumari, Y., Goh, B.H., Jaiswal, Y., Rosli, R., Leonard, W.* & Shaikh, M. F.* (2016). Acute toxicity profiling of the ethyl acetate fraction of Swietenia macrophylla seeds and in-vitro neuroprotection studies. Saudi Pharmaceutical Journal. (ISI Cited, IF: 2.233, Q3)
Ser, H.L., Palanisamy, U.D., Yin, W.F., Chan, K.G., Goh, B.H.* & Lee, L.H.* (2016). Streptomyces malaysiense sp. nov.: A novel Malaysian mangrove soil actinobacterium with antioxidative activity and cytotoxic potential against human cancer cell lines. Scientific Reports. (doi:10.1038/srep24247) (ISI Cited, IF: 5.578, Q1)
Ser, H.L., Law, J.W.F., Chaiyakunapruk, N., Jacob, S.A., Palanisamy, U.D., Chan, K.G., Goh, B.H.* & Lee, L.H.* (2016). Fermentation conditions that affect clavulanic acid production in Streptomyces clavuligerus: a systematic review. Frontiers in Microbiology. (doi: 10.3389/fmicb.2016.00522) (ISI Cited, IF: 3.989, Q1)
Tan, H.L., Chan, K.G., Pusparajah, P., Lee, L.H.* & Goh, B.H.* (2016). Gynura procumbens: An overview of the biological activities. Frontiers in Pharmacology. 7:52. (doi: 10.3389/fphar.2016.00052) (ISI Cited, IF: 3.8, Q1)
Chan, W.K., Tan Loh, T.H., Chan, K.G., Lee, L.H.* & Goh, B.H. *(2016). Nerolidol: A sesquiterpene alcohol with multi-faceted pharmacological and biological activities. Molecules. (ISI Cited, IF: 2.416, Q2)
Tan Loh, T. H, Chan, K. G., Lee, L. H.* & Goh, B. H.* (2016). Steptomyces bacteria as potential probiotics in aquaculture. Frontiers in Microbiology,7:79. (ISI Cited, IF: 3.989, Q1)
Tan Loh, T. H, Ser, H. L., Yin, W. F., Chan, K. G., Lee, L. H.*, & Goh, B. H.* (2015). Investigation of antioxidative and anticancer potentials of Streptomyces sp. MUM256 isolated from Malaysia mangrove soil. Frontiers in Microbiology, 6, 1316. (ISI Cited, IF: 4, Q1)
Ser, H. L., Nurul, S. A. M., Yin, W. F., Chan, K. G., Goh, B. H.*, & Lee, L. H.* (2015). Evaluation of antioxidative and cytotoxic activities of Streptomyces pluripotens MUSC 137 isolated from mangrove soil in Malaysia. Frontiers in Microbiology. (ISI Cited, IF:4, Q1)
Lau, W. K., Goh, B. H., Habsah, A. K., Alexander Chong S. C., & Tengku, S. T. M.* (2015). Potent PPARγ Ligands from Swietenia macrophylla Are Capable of Stimulating Glucose Uptake in Muscle Cells. Molecules. (ISI Cited, IF: 2.416, Q2)
Hadi, S., Kamarudin, M.N.A., Chan, C.K., Goh, B.H. & Habsah, A.K.* (2015). SMEAF attenuates the production of pro-inflammatory mediators through the inactivation of Akt-dependent NF-kappa B, p38 and ERK1/2 pathways in LPS-stimulated BV-2 microglia cells. Journal of Functional Foods. (ISI Cited, IF:4.48,  Q1)
Ser, H. L., Palanisamy, U. D., Yin, W. F., Malek, A. S., Chan, K. G., Goh, B. H.* & Lee, L. H.* (2015). Presence of antioxidative agent, Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro- in newly isolated Streptomyces mangrovisoli sp. nov. Frontiers in Microbiology, 6:854. (doi: 10.3389/fmicb.2015.00854) (ISI-Cited, IF: 4, Q1)
Chan, C. K., Hadi, S., Goh, B. H., & Kadir, H. A.* (2015). Elephantopus scaber induces apoptosis through ROS-dependent mitochondrial signaling pathway in HCT116 human colorectal carcinoma cells. Journal of Ethnopharmacology. (doi:10.1016/j.jep.2015.03.072) (ISI Cited, IF: 2.998, Q1)
Ser, H. L., Nurullhudda, Z., Uma,  D. P., Goh, B. H., Yin, W. F., Chan, K. G. & Lee, L. H.* (2015). Streptomyces gilvigriseus sp. nov., a novel actinobacterium isolated from mangrove forest soil. Antonie van Leeuwenhoek, 1-10. (doi: 10.1007/s10482-015-0431-5) (ISI Cited, IF: 1.806, Q3)
Tan Loh, T.H., Lee, L.H., Yin, W.F., Chan, C.K., Habsah, A.K., Chan, K.G. & Goh, B.H.* (2015). Traditional uses, phytochemistry and bioactivities of Cananga odorata (Ylang-ylang). Evidence-Based Complementary and Alternative Medicine. (ISI Cited,  IF: 1.880, Q2)
Goh, B. H., Chan, C. K. Mohammad, N. A. K., & Kadir, H. A.* (2014). Swietenia macrophylla King induces mitochondrial-mediated apoptosis through p53 upregulation in HCT116 colorectal carcinoma cells. Journal of Ethnopharmacology, 168: 291-304. (ISI cited, IF: 2.939, Q1)
Soheil, Z. M., Muhamad, N.A.K, Chan, C.K., Goh, B.H. and Habsah, A.K.* (2014). Biological activities and phytochemicals of Loranthus parasiticus Merr: A Review. The American Journal of Chinese Medicine, 42(1). (ISI-cited, IF: 2.755, Q1)
Arulsamy, A., Goh, B. H. and Shaikh, M. F.* (2014). Current status of epilepsy in Malaysia and way ahead. International Journal of Pharmacy and Pharmaceutical Sciences, 7(1). (Scopus-cited)
Lee, L. H.*, Zainal, N., Azman, A. S., Eng, S. K., Goh, B. H., Yin, Y. F., Mutalib, N. S. and Chan, K. G. (2014). Diversity and Antimicrobial Activities of Actinobacteria Isolated from Tropical Mangrove Sediments in Malaysia. The Scientific World Journal. (ISI-cited, IF: 1.219, Q2)
Soheil, Z. M., Goh, B. H., Chan, C.K., Shabab, T. and Habsah, A.K.* (2013). Biological Activities and Phytochemicals of Swietenia macrophylla King. Molecules, 18: 10465-10483. (ISI-cited, IF: 2.095, Q2)
Chan, C. K., Goh, B. H., Mohammad, N. A. K., & Kadir, H. A.* (2012). Aqueous fraction of Nephelium ramboutan-ake Rind induced mitochondrial-mediated apoptosis in HT-29 human colorectal adenocarcinoma cells. Molecules, 17(6), 6633-6657. (ISI-cited, IF: 2.428, Q2)
Wong, D. Z. H., Kadir, H. A.*, Lee, C. L., & Goh, B. H. (2012). Neuroprotective properties of Loranthus parasiticus aqueous fraction against oxidative stress-induced damage in NG108-15 cells. Journal of Natural Medicines, 1-8. (ISI-cited, IF: 1.516, Q3)
Goh, B. H., & Kadir, A.* (2011). In vitro cytotoxic potential of Swietenia macrophylla King seeds against human carcinoma cell lines. Journal Medicinal Plants Research, 5(8), 1395-1404. (ISI-cited, IF: 0.879, Q4)
Goh, B. H., Abdul Kadir, H., Abdul Malek, S., & Ng, S. W.* (2010). Swietenolide diacetate from the seeds of Swietenia macrophylla. Acta Crystallographica Section E: Structure Reports Online, 66(6), o1396-o1396. (ISI-cited, IF: 0.413, Q4)

(D) CONFERENCE PROCEEDINGS (REFEREED ONLY)

Tan Loh, T.H., Ser, H.L., Yin, W.F., Chan, K.G., Lee, L.H. & Goh, B.H. (2016). "MUM256: A Malaysia mangrove soil Streptomyces strain as a potential source of antioxidant and anti-cancer agent", International Conference on Molecular Biology & Biotechnology in conjunction with The 23rd MSMBB Scientific Meeting (March 2016), at Connexion@Nexus, Bangsar South City, Kuala Lumpur. 
Tan Loh, T.H., Ser, H.L., Yin, W.F., Chan, K.G., Lee, L.H. & Goh, B.H. (2016). "MUM256: A Malaysia mangrove soil Streptomyces species with apoptosis-inducing properties in cancer cells", The Australian Society for Microbiology: New Frontiers (3-6 July 2016), at Perth Convention & Exhibition Centre, Perth, Australia.
Law, J.W.F, Ser, H.L., Goh, B.H. &  Lee, L.H. (2016). "The potential of Streptomyces as biocontrol agent against rice blast fungus, Magnaporthe oryzae (Pyricularia oryzae)", The Australian Society for Microbiology: New Frontiers (3-6 July 2016), at Perth Convention & Exhibition Centre, Perth, Australia.
Ser, H.L., Uma, D.P., Yin, W.F., Chan, K.G., Goh, B.H. &  Lee, L.H. (2016). "A novel actinobacterium, Streptomyces malaysiense sp. nov., isolated from Malaysian mangrove soil with cytotoxic potential against cancer cell lines", The Australian Society for Microbiology: New Frontiers (3-6 July 2016), at Perth Convention & Exhibition Centre, Perth, Australia. 
Tharveena, R., Saatheeyavaane, B., Shaikh, F., Kumari, Y., Othman, I., Goh, B.H., Amin, M.S.A.M., Aman, S.A.M. & Hassan, Z. (2015). "The effect of ethanolic Orthosiphon stamineus extract on learning & memory in chronic cerebral hypoperfusion induced cognitive impairment in rats", CDR Mini Symposium on Drug Addiction & Neurodegeneration (November 2015), at University Sains Malaysia.
Ser, H.L., Marilyn, T., Uma, D.P., Yin, W.F., Chan, K.G., Goh, B.H. & Lee, L.H. (2015). "Exploring the genome sequence of a novel Actinobacterium with bioactive potential, Streptomyces mangrovisoli MUSC149T", 22nd Annual Scientific Meeting (September 2015), RMIC, University Malaya, Kuala Lumpur, Malaysia.
kumari, Y., Goh, B.H. & Shaikh, F. (2015). "Piper betel, a novel Melatonin agonist for the treatment of sleep disorder", International Conference on Biomedical & Health Sciences Research (January 2015), Putrajaya, Malaysia.
Tengku, S.T.M., Habsah, A.K., Goh, B.H., Lau, W.K., Chong, A.S.C. (2013). “Effect of Naturally Identified   Compound from Swietenia macrophylla on PPARγ Activated Adipocyte Differentiation and Gene Expression”, 12th International UMT Annual Symposium (UMTAS 2013)(October 2013), Permai Hotel Kuala Terengganu, Malaysia.
Goh, B.H. & Habsah, A.K. (2011). “Ethyl Acetate fraction of Swietenia macrophylla King triggers apoptosis on Human Colon Carcinoma cell lines HCT116",  16th Biological Sciences Graduate Congress (BSGC) (12-14th December 2011), National University of Singapore, Singapore.
Goh, B.H. & Habsah, A.K. (2010). “Cytotoxicity and potential mechanisms studies of Swietenia macropylla King and its chemical constituents against human cancer cell lines”, UK-Malaysia Symposium on Drug Discovery and Development for Cancer (February 2010), Grand Dorsett Hotel, Subang, Malaysia.
 Goh, B.H. & Habsah, A.K. (2009). “Antioxidant and cytotoxicity effect of plant Swietenia macrophylla”,  14th Biological Sciences Graduate Congress (BSGC) (10-12th December 2009), Chulalongkorn University, Bangkok, Thailand.
Lee, C.L., Goh, B.H. & Habsah, A.K. (2009).  “Neuroprotective effect of plant Ficus deltoidea in hydrogen peroxide induced damage of NG108-15 Cells and its possible mechanisms”, 20th Intervarsity Biochemistry Seminar (21st March 2009), University of Putra Malaysia, Malaysia.
Goh, B.H., Habsah, A.K., Hong, S.L., Lee, G.S. & Malek, S.N.A. (2009). "Antioxidant and cytotoxicity activities of plant Swietenia macrophylla King", International Conference of Natural Product and Traditional Medicines 2009 (ICNPTM’09) (16-18th October 2009), Northwest University, Xi’an City, China.
Lee, C.L., Daniel, W.Z.H., Goh, B.H. & Habsah, A.K. (2009). “Protective Effects of Ficus deltoidea Jack on Hydrogen Peroxide-Induced Apoptosis in NG108-15 Neuroblastoma Cells”,  International Conference of Natural Product and Traditional Medicines 2009 (ICNPTM’09) (16-18th October 2009), Northwest University, Xi’an City, China.
Lee, C.L., Maizatul, H.B.O., Goh, B.H. & Habsah, A.K. (2008). “The antioxidant activities and total phenolic compounds of plant Ficus deltoidea”,33rd Annual Conference of Malaysian Society for Biochemistry and Molecular Biology  (27-28th August 2008). Istana Hotel, Kuala Lumpur, Malaysia.  
Goh. B.H., Goh, B.H. &Habsah Abdul Kadir (2008). "Antioxidant and cytotoxicity of Cibotium barometz & Swietenia macrophylla", 19th Intervarsity Biochemistry Conference, University Tunku Abdul Rahman (UTAR), Petaling Jaya, Kuala Lumpur.
  1. Guest Associate Editor, Frontiers in Pharmacology
  2. Review Editor, Frontiers in Microbiology
  3. Guest Associate Editor, Frontiers in Microbiology
  4. Review Editor, Frontiers in Pharmacology
  5. Editorial Board Member, Journal of clinical Practice and Health Sciences
  6. Biochemistry Program Curriculum Review Panel, University Malaya
  7. Reviewer, Journal of Ethnopharmacology
  8. Reviewer, General and Comparative Endocrinology
  9. Elsevier Advisory Panel, Elsevier
  10. Member, Malaysia Society for Biochemistry & Molecular biology (MSBMB)
  11. Member, Council for Nutritional and Environmental Medicine (CONEM)

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