Dr. Thet Thet Htar

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Contact Details

BPharm (Hons) (Cardiff), MRPharmS (UK), PhD (Cardiff)
Lecturer (Medicinal Chemistry, Pharmacy)

Office: Building 2, Level 5, Room 30
Tel: +603 5514 4912
Fax: +603 5514 6364
Email: thet.thet.htar@monash.edu

Biodata

Dr. Thet graduated with a Bachelor of Pharmacy (Honours) in 1999 from the University of Wales in Cardiff, United Kingdom. She then underwent her pre-registration training at West Wales General Hospital in Carmarthen, Wales and subsequently passed the board examinations in 2000, gaining registration with the Royal Pharmaceutical Society of Great Britain (RPSGB). She then went on to pursue her doctorate in Medicinal Chemistry (Antiviral drug design), also at the University of Wales in Cardiff, which she completed in early 2004. During that same time, as part of her continuing professional development, Dr. Thet also served as a community pharmacist on a sessional basis in several pharmacies in the United Kingdom from 2000 – 2003. Soon after completing her PhD, she was appointed an academic lecturer in medicinal chemistry and a school representative in research at the School of Pharmacy, Faculty of Medical Sciences, UCSI University, Malaysia, where she served for almost 5 years. Dr.Thet joined Monash University, Malaysia in March 2009.

Areas of Expertise

  1. Medicinal Chemistry
  2. Organic Synthesis
  3. Natural Products
  4. Drug design in antiviral and anticancer agents

Academic Qualifications

Doctor of Philosophy (PhD)
InstitutionUniversity of Wales, Cardiff, United Kingdom
Year Awarded2004
 
Bachelor of Pharmacy (Hons)
InstitutionUniversity of Wales, Cardiff, United Kingdom
Year Awarded1999

(A)  BOOK CHAPTERS

T. T. Htar and G. A. Akuwoah (2010). Global medicinal plants with anti-HIV activities. Potential & Challenges. Researches in Bioactive Natural Products. Studium Press LLC, USA, 1, 323
T. T. Htar and G. A. Akuwoah (2010). Free radical scavenging activity from methanolic bark extract of Limonia acidissima. Extraction, Isolation & Characterization. Researches in Bioactive Natural Products. Studium Press LLC, 4, 299.

(B) SCHOLARLY JOURNALS (REFEREED ONLY)

F.Y.Lee, T.T.Htar and G.A.Akowuah (2015). ATR-FTIR and Spectrometric Methods for the assay of crocin in commercial saffron spices (Crocus Savitus L.)
T.T.Htar and G.A.Akowuah (2014). Therapeutic properties of saffron and its chemical constituents. Journal of Natural Products.
T. T. Htar and G. A. Akuwoah (2010). Free radical scavenging activity from methanolic bark extract of Limonia acidissima. Extraction, Isolation & Characterization. Researches in Bioactive Natural Products. Studium Press LLC, 4, 299
T. T. Htar and G. A. Akuwoah (2010). Global medicinal plants with anti-HIV activities. Potential & Challenges. Researches in Bioactive Natural Products. Studium Press LLC, USA, 1, 323.
T. T. Htar and J. F. F. Weber (2010). Design and synthesis of modified resveratrol analogues with potential apoptosis activity. European Journal of Cancer Supplements, 8 (7), 96.
C. Simons, Q. Wu and T. T. Htar (2005). Recent advances in antiviral nucleoside and nucleotide therapeutics. Current Topics in Medicinal Chemistry, 5 (13), 1191
N. Kifli, T. T. Htar, E. De Clercq, J. Balzarini and C. Simons (2004). Novel bicyclic sugar modified nucleosides: Synthesis, Conformational analysis and antiviral evaluation. Bioorganic & Medicinal Chemistry, 12 (12), 3247

(C) CONFERENCE PROCEEDINGS (REFEREED ONLY)

T. T. Htar and J. F. F. Weber (2010). Design and synthesis of modified resveratrol analogues with potential apoptosis activity. European Journal of Cancer Supplements, 8 (7), 96.
T. T. Htar,  J. F. F. Weber and S. A. A. Shah (2011). Design and synthesis of modified resveratrol analogues with potential apoptosis activity. BIT’s 9th Annual Congress of International Drug Discovery Science and Technology, 72. 
T. T. Htar and G. A. Akowuah (2011). Saffron (crocus sativus l.) as an alternative medicine. International conference on Traditional medicine (CONTRAMED), 49
T. T. Htar and G. A. Akuwoah (2007). Radical scavenging activity from methanolic extract of Limonia acidissima. Abstract book of Commonwealth Pharmaceutical Association and Malaysian Pharmaceutical Society Pharmacy Scientific Conference, 108.
T. T. Htar and C. Simons (2004). Design and synthesis of conformationally restrained novel bicyclic nucleosides. Abstract book of 4th UiTM-MPS Pharmacy Scientific Conference, 93
C.S.Chew, W.K.Chin, M.Jasamai, and T.T.Htar. Optimisation and synthesis of structurally modified 18-β-Glycyrrhetinic acids as potential 11β-HSD1 inhibitors. National Biotechnology seminar 2013. Penang.
T.T.Htar, N.Yunus, M.Jasamai, C.Y.Lee, K.B.A.Kadir. In Silico Search for Steroidal Based 11beta-Hydroxysteroid Dehydrogenase (Type 1) Inhibitor. IDDST 2013. Haikou, China.

Local Grants

TitleIdentification of the pharmacophoric groups of an ideal GPER-1 ligand and its interaction mechanism with the receptor in breast cancer cells
InvestigatorsDr. Thet Thet Htar, Dr. Chuah Lay Hong, Alice,  Assoc Prof. Rakesh Naidu, Dr. Nafees Ahemad 
Funding (Start & End Year)2015-2018
Funding Body/OrganisationFRGS/MOHE
Funding AmountRM145,000
 
TitleDevelopment of selective 11beta-hydroxysteroid dehydrogenase (Type 1) inhibitor as a potential therapeutic agents for obesity
InvestigatorsDr. Thet Thet Htar, Dr. Malina Jasamai, Dr. Lee Chooi Yeng & Prof Khalid Kadir
Funding (Start & End Year)2012-2014
Funding Body/Organisation eScience/MOSTI
Funding AmountRM186,500
 

International Grants

TitleUse of guided active learning in thermodynamics to improve the performance of pharmacy students
InvestigatorsDr. Thet Thet Htar & Dr. Nafees Ahemad
Funding (Start & End Year)2016
Funding Body/Organisation                                       Monash Education Academy, Australia
Funding AmountAUD5,000

Membership in Associations and International Bodies

Name of Association/International BodyRoyal Pharmaceutical Society of Great Britain      RoleMemberDuration of membership - Month/YearFeb - 2017

Name of Association/International BodyRoyal Pharmaceutical Society of Great Britain
RoleMember
Duration of membership - Month/YearFeb - 2017