Dr. Ooi Ean Hin
Dr Ooi Ean Hin obtained his PhD in Mechanical Engineering from Nanyang Technological University in 2009. In 2010, he was employed as a Research Fellow in the College of Medical and Dental Sciences, University of Birmingham as part of the Wellcome Trust Fellowship Bridging Award. Prior to his appointment in Monash University Malaysia, he was a Postdoctoral Research Fellow in Wessex Institute of Technology and University of Oxford, where he worked on projects funded by the European Union under the 7th Framework Program. Dr Ooi is involved in cross-disciplinary research that applies fundamental engineering principles to solve complex biophysical and physiological problems that relate to the medical world.
- Doctor of Philosophy in Mechanical Engineering, Nanyang Technological University, 2009
- Degree in Mechanical Engineering, Universiti Teknologi Malaysia, 2005
Member of National Professional Bodies
- Board of Engineers Malaysia (BEM), Graduate Member
Member of International Professional Bodies
- Institute of Mechanical Engineers (IMechE), Chartered Engineer
Dr Ooi’s research interest focuses on elucidating fundamental mechanisms of various biophysical and physiological problems that are related to healthcare through mathematical and computational modelling. These studies are aimed at facilitating the diagnosis of diseases, improving treatment techniques and formulating solutions to unanswered medical problems.
Dr Ooi’s primary research interest is in the field of ophthalmology, with particular emphasis on the disease glaucoma. Glaucoma presents a very interesting and challenging engineering problem as it involves different engineering aspects, such as the hydrodynamics of aqueous humor located at the anterior segment of the eye and the biomechanics of the optic nerve head located towards the posterior segment. Various aspects of the disease – from the diagnosis to its treatment – can be improved through a fundamental understanding of the different mechanics that are involved.
Dr Ooi is also actively involved in the understanding of thermal ablation treatment of cancer, such as radiofrequency ablation and cryoablation. Mathematical and computational modelling techniques are used not only to understand the physiological responses of tissues to heat, but also to optimize the treatment outcome of these different treatment modalities.
Dr Ooi maintains a strong interest in the development of mesh reduction numerical methods, such as the boundary element method and meshless methods. He is one of the pioneers of the meshless technique, radial basis integral equation method that utilizes integral equations and radial basis functions to solve partial differential equations.
Title: Biomechanics and Biofluid Dynamics of Glaucomatous Eyes
Title: A Mathematical Framework For The Radiofrequency Ablation and Cryoablation Treatment Of Cancer
Although surgical resection remains the ‘gold standard’ for cancer treatment, minimally invasive thermal ablation (MITA) treatments such as radiofrequency ablation (RFA) and cryoablation are gaining wider acceptance primarily due to its minimal invasiveness, low morbidity and the ability to treat patients in an outpatient setting. Nevertheless, designing a successful MITA treatment protocol is often very difficult due to the outcome being highly dependent on the experience of the interventional radiologists. The decision on the treatment protocol usually involves discussion among several interventional radiologists (IRs), with the process taking up to 30 minutes in severe cases. If the protocol is unsuccessful, further treatments will have to be planned that can involve excessive patient exposure to hazardous CT scan radiations. The main objective of the proposed research is to develop a prototype computational platform based on established mathematical framework for modelling thermophysiological processes that can simulate the outcome of RFA and cryoablation treatment of cancer.
MEC2405 - Thermodynamics
MEC3456 - Engineering Computational Analysis
MEC4401 - Final Year Project
MEC4402 - Final Year Project-Thesis
- Unlocking the biomechanical interactions inside the human eye: a first step towards understanding glaucoma, Ooi Ean Hin, Hung Yew Mun, Amir Samsudin, Norlina Ramli, 2014-2017, Ministry of Education Malaysia, RM82,000
- Development of a prototype computational platform for assisted interventional planning of radio frequency ablation and cryoablation treatment of cancer, Ooi Ean Hin, Foo Ji Jinn, Iman Yi Liao, Shalini Nair, Ahmad Faizal Mohd Ali, 2017 – 2019, Ministry of Science, Technology and Innovation Malaysia, RM186,758
- Extracorporeal perfusion of the ex vivo liver to mimic the pressure environment of the liver in vivo: application to saline infusion study, Ooi Ean Hin, Narendra Pamidi, 2015, Advanced Engineering Platform, Monash University Malaysia, RM10,000
- Computational modelling technique as an effective tool for studying saline-infused radiofrequency ablation treatment of liver cancer, Ooi Ean Hin, Narendra Pamidi, 2014, Advanced Engineering Platform, Monash University Malaysia, RM7,500
Loke Chai Yee
Study of ocular biomechanics: an application to glaucoma
Monash University Malaysia
Antony Kho Seng Khai
Development of mathematical and computational framework for soft tissue mechanics during saline infusion
Monash University Malaysia
A numerical modelling approach to the optimization of saline-infused radiofrequency ablation
Monash University Malaysia
- Fellowship Bridging Award - Wellcome Trust, 2010