Dr. Patrick Tang Siah Ying

Senior Lecturer
School of Engineering

patrick.tang@monash.edu
+603 5514 4435
Room 5-5-15
ORCID

Personal statement

Dr Patrick is currently a Senior Lecturer at Monash University Malaysia. He holds a PhD in Chemical Engineering from The University of Nottingham. His research interests focus on cavitation technology and nano/microencapsulation and controlled delivery of bioactive ingredients. One of his great doctoral work was investigating the use of novel liquid whistle hydrodynamic cavitation reactor technology which will provide innovating and exciting perspectives for modern food and pharmaceutical industry that is looking for significant and competitive process improvement with sonochemistry. In July 2011, he received the Research Led Fund Award from the University of Nottingham (UoN). In May 2012, he had been selected as best poster presenter for Postgraduate Research Poster Competition, Faculty of Engineering, UoN. His interdisciplinary work had resulted in a fruitful collaboration with Tissue Engineering Centre, UKM Hospital. Patrick is an active author, with 3 book chapters and 15 ISI-indexed publications (9 Q1 papers). He is currently supervising 4 full-time PhD students and acting as an associate supervisor for another 2. Because of his outstanding research achievements in bio-nano engineering, Patrick has been honoured with Young Chemical Engineer at prestigious IChemE Malaysia Awards 2014. In Jan 2019, he has been awarded a visiting fellowship by Chulalongkorn University to undertake collaborative research at Center of Excellence in Particle Technology. Presently, Patrick is the principal investigator for one government grant and one industry grant. Additionally, he has established collaborative industry-driven projects with Malaysia-based multinational companies (CCM Innovative Solutions Sdn. Bhd and Sime Darby Plantation Sdn Bhd), working cooperatively in the field of functional polymeric coating and sustainable palm oil processing technology.

Academic degrees

  • Doctor of Philosophy in Chemical Engineering, University of Nottingham, UK, 2012
  • Degree in Chemical Engineering (Hons), University of Malaya, 2008

Professional affiliation

Member of National Professional Bodies

  • Board of Engineers Malaysia (BEM), Graduate Member
  • Malaysian Oil Scientists and Technologists Association (MOSTA), Member

Member of International Professional Bodies

  • Institution of Chemical Engineers (IChemE), Associate Member
  • Asean Society for Colloid and Surface Science (ASCASS), Associate Member

Research Interests

My research areas are in colloid and polymer science. Particularly, I am interested in the encapsulation and controlled release technologies based on functional colloid micro or nanoemulsions. Together with my research group and collaborators, we have been actively working on the design and development of smart, biodegradable and biocompatible nanoparticle-stabilized emulsions as new encapsulation and controlled delivery systems of bioactive compounds and phytonutrients for modern nutraceutical and pharmaceutical applications. On polymer side, I have students working on new self-healing rubber and polymeric microcapsules with tunable properties. These materials have numerous applications in consumer products, biomedical, agriculture and aerospace.

Research projects

Title: Ultrasonic Micro/Nanoencapsulation Technologies for Sustainable Food and Pharmaceutical Industries

Encapsulation and delivery of bioactive and functional lipophilic constituents in the form of oil-in-water emulsions have been a focus of intensive research within the food and pharmaceutical industries. Generally, the formation of emulsions could be achieved by using inline rotor/stator mixers, colloid mills and high pressure homogenizers, etc. However, most of the traditional methods usually fail to provide a satisfactory control over the particle size distribution and often result in poor dispersion stability. To date, ultrasound (US) cavitation technology has emerged as an energy-efficient and promising technique for the generation of highly uniform and stable food and pharmaceutical emulsions. The micro-turbulent implosions of cavitation bubbles tear-off primary coarse oil droplets to micro/nano-scale, spontaneously leading to the formation of fine emulsion droplets. The main aim of this project is to explore a novel yet innovative sonoreactor design in the facile and sustainable production of surfactant-free emulsions. Experimental and modelling investigations are the core elements of this project.

Education

Units taught

CHE3172 - Nanotechnology and Materials 1

CHE3163 - Sustainable Processing I

Journal

Siva, Sangeetaprivya P.; Kow, Kien Woh; Chan, Chung Hung; Tang, Siah Ying; Ho, Yong Kuen (2019) Prediction of droplet sizes for oil-in-water emulsion systems assisted by ultrasound cavitation: Transient scaling law based on dynamic breakup potential, Ultrasonics Sonochemistry, (348-358), Volume: 55, Issue Number: 13504177, 10.1016/j.ultsonch.2018.12.040

Low, Liang Ee; Wong, See Kiat; Tang, Siah Ying; Chew, Chien Lye; De Silva, Hithanadura Ashcharya; Lee, Jacqueline May Vern; Hoo, Cheng Hao; Kenrick, Khor (2019) Production of highly uniform Pickering emulsions by novel high-intensity ultrasonic tubular reactor (HUTR), Ultrasonics Sonochemistry, (121-128), Volume: 54, Issue Number: 13504177, 10.1016/j.ultsonch.2019.02.008

Low, Liang Ee; Tan, Loh Teng Hern; Goh, Bey Hing; Tey, Beng Ti; Ong, Boon Hoong; Tang, Siah Ying (2019) Magnetic cellulose nanocrystal stabilized Pickering emulsions for enhanced bioactive release and human colon cancer therapy, International Journal of Biological Macromolecules, (76-84), Volume: 127, Issue Number: 01418130, 10.1016/j.ijbiomac.2019.01.037

Low, Liang Ee; Tey, Beng Ti; Ong, Boon Hoong; Tang, Siah Ying (2018) A facile and rapid sonochemical synthesis of monodispersed Fe<inf>3</inf>O<inf>4</inf>@cellulose nanocrystal nanocomposites without inert gas protection, Asia-Pacific Journal of Chemical Engineering, Volume: 13, Issue Number: 19322135, 10.1002/apj.2209

Ng, Hon Wei; Lee, Micky Fu Xiang; Chua, Gek Kee; Gan, Bee Koon; Tan, Wen Siang; Ooi, Chien Wei; Tang, Siah Ying; Chan, Eng Seng; Tey, Beng Ti (2018) Size-selective purification of hepatitis B virus-like particle in flow-through chromatography: Types of ion exchange adsorbent and grafted polymer architecture, Journal of Separation Science, (2119-2129), Volume: 41, Issue Number: 16159306, 10.1002/jssc.201700823

Low, Liang Ee; Tey, Beng Ti; Ong, Boon Hoong; Tang, Siah Ying (2018) Unravelling pH-responsive behaviour of Fe<inf>3</inf>O<inf>4</inf>@CNCs-stabilized Pickering emulsions under the influence of magnetic field, Polymer, (93-101), Volume: 141, Issue Number: 00323861, 10.1016/j.polymer.2018.03.001

Low, Liang Ee; Tey, Beng Ti; Ong, Boon Hoong; Chan, Eng Seng; Tang, Siah Ying (2017) Palm olein-in-water Pickering emulsion stabilized by Fe<inf>3</inf>O<inf>4</inf>-cellulose nanocrystal nanocomposites and their responses to pH, Carbohydrate Polymers, (391-399), Volume: 155, Issue Number: 01448617, 10.1016/j.carbpol.2016.08.091

Tan, Khang Wei; Tang, Siah Ying; Thomas, Renjan; Vasanthakumari, Neela; Manickam, Sivakumar (2016) Curcumin-loaded sterically stabilized nanodispersion based on non-ionic colloidal system induced by ultrasound and solvent diffusion-evaporation, Pure and Applied Chemistry, (43-60), Volume: 88, Issue Number: 00334545, 10.1515/pac-2015-0601

Low, Liang Ee; Tey, Beng Ti; Ong, Boon Hoong; Chan, Eng Seng; Tang, Siah Ying (2016) Dispersion stability, magnetivity and wettability of cellulose nanocrystal (CNC)-dispersed superparamagnetic Fe<inf>3</inf>O<inf>4</inf> nanoparticles: impact of CNC concentration, RSC Advances, (113132-113138), Volume: 6, 10.1039/c6ra16109j

Ong, Wan Ding; Tey, Beng Ti; Quek, Siew Young; Tang, Siah Ying; Chan, Eng Seng (2015) Alginate-Based Emulsion Template Containing High Oil Loading Stabilized by Nonionic Surfactants, Journal of Food Science, (E93-E100), Volume: 80, Issue Number: 00221147, 10.1111/1750-3841.12729

Sivakumar, Manickam; Tang, Siah Ying; Tan, Khang Wei (2014) Cavitation technology - A greener processing technique for the generation of pharmaceutical nanoemulsions, Ultrasonics Sonochemistry, (2069-2083), Volume: 21, Issue Number: 13504177, 10.1016/j.ultsonch.2014.03.025

Tang, Siah Ying; Sivakumar, Manickam; Nashiru, Billa (2013) Impact of osmotic pressure and gelling in the generation of highly stable single core water-in-oil-in-water (W/O/W) nano multiple emulsions of aspirin assisted by two-stage ultrasonic cavitational emulsification, Colloids and Surfaces B: Biointerfaces, (653-658), Volume: 102, Issue Number: 09277765, 10.1016/j.colsurfb.2012.08.036

Tang, Siah Ying; Sivakumar, Manickam (2013) A novel and facile liquid whistle hydrodynamic cavitation reactor to produce submicron multiple emulsions, AIChE Journal, (155-167), Volume: 59, Issue Number: 00011541, 10.1002/aic.13800

Tang, Siah Ying; Shridharan, Parthasarathy; Sivakumar, Manickam (2013) Impact of process parameters in the generation of novel aspirin nanoemulsions - Comparative studies between ultrasound cavitation and microfluidizer, Ultrasonics Sonochemistry, (485-497), Volume: 20, Issue Number: 13504177, 10.1016/j.ultsonch.2012.04.005

Tang, Siah Ying; Sivakumar, Manickam; Ng, Angela Min Hwei; Shridharan, Parthasarathy (2012) Anti-inflammatory and analgesic activity of novel oral aspirin-loaded nanoemulsion and nano multiple emulsion formulations generated using ultrasound cavitation, International Journal of Pharmaceutics, (299-306), Volume: 430, Issue Number: 03785173, 10.1016/j.ijpharm.2012.03.055

Tang, Siah Ying; Sivakumar, Manickam (2012) Design and evaluation of aspirin-loaded water-in-oil-in-water submicron multiple emulsions generated using two-stage ultrasonic cavitational emulsification technique, Asia-Pacific Journal of Chemical Engineering, Volume: 7, Issue Number: 19322135, 10.1002/apj.664

Tang, Siah Ying; Manickam, Sivakumar; Wei, Tan Khang; Nashiru, Billa (2012) Formulation development and optimization of a novel Cremophore EL-based nanoemulsion using ultrasound cavitation, Ultrasonics Sonochemistry, (330-345), Volume: 19, Issue Number: 13504177, 10.1016/j.ultsonch.2011.07.001

Local grants

  • Assessing the Role of Sulfate Group in Single Step In-situ Formation of Fe3O4-CNC Bionanocomposites and its Application for Remote Controlled Drug Release, Tang SY (PI), Chan ES, Ong BH, Wong TW, 2017-2019, Ministry of Higher Education (MOHE), RM 89,978
  • Functional Polymeric Coating for Gloves, Tang SY (PI), Chan ES, Yeoh CT, Khew MC, 2016-2019, CCM Innovative Solutions Sdn Bhd, RM180, 000
  • Achieving Target Emulsion Drop Size Distribution and Droplet Stability for Cellulose Nano-Crystal (CNC) Based Pickering Emulsions Using the Population Balance Technique, Ho YK (PI), Tang SY, Kow KK, Chan CH, EC Abdullah, 2017-2019, Ministry of Higher Education (MOHE), RM109,800

Current supervision

PhD

Abdul Hasif Bin Abd Rahim (Main supervision)

Development of Core-shell Microcapsules for Polymeric Functional Coating

April 2017 - Present

Monash University Malaysia

Wong See Kiat (Main supervision)

Development of Pickering Emulsions stabilized by Biocompatible Food Protein-modified CNCs and Their Potential as Bioactive Delivery Systems

Feb 2018 - Present

Monash University Malaysia

Mervin Chew Chien Lye (Main supervision)

Production, Characterisation and Applications of Biological Aqueous Solution-treated Crude Palm Oil

March 2018 - Present

Monash University Malaysia

Janarthanan Supramanian (Main supervision)

Development and Characterisation of Self-healable ENR based on Plant-derived CNFs with tunable mechanical properties

May 2018 - Present

Monash University Malaysia

Sangeetaprivya P.Siva (Co-supervision)

Achieving Target Emulsion Drop Size Distribution and Droplet Stability for the Formation of Cellulose Nanocrystal (CNC)-based Pickering Emulsions via Ultrasound Emulsification Using the Population Balance Technique

2018 - Present

Monash University Malaysia

Kristian Hendrata (Co-supervision)

A Facile Method of Surface Modification Based on SiO2 and Octadecyltrichlorosilane for the Fabrication of Transparent Superhydrophobic Coating

2017 - Present

Monash University Malaysia

Completed supervision

PhD

Low Liang Ee (Main supervision)

Development of Magneto-responsive Pickering Emulsion based on Cellulose Nanocrystal as Novel Controlled Drug Delivery Carrier

2015-2018

Monash University Malaysia

Master

Ng Hon Wei (Co-supervision)

Poly (ethylene glycol methacrylate) polymer modified ion exchange resin for the negative chromatography of hepatitis B virus-like particle from Escherichia coli homogenate

2015-2017

Monash University Malaysia

Local Award/Recognition/Exhibition/Stewardship

  • Award (Winner) for Young Chemical Engineer in Academia - IChemE Malaysia, 2014
  • Recognition (Highly Commended) in Palm Oil Industry Award - IChemE Malaysia, 2018

International Award/Recognition/Exhibition/Stewardship

  • Chulalongkorn University Visiting Fellowship - Chulalongkorn University, Thailand, 2019