Prof. Tey Beng Ti

Head of Discipline (Chemical Engineering)
School of Engineering

tey.beng.ti@monash.edu
+603 5514 6240
Room 5-4-65
ORCID

Personal statement

Professor Beng Ti  Tey has joined School of Engineering, Monash University Malaysia in 2011, and  is currently the Director of Advanced Engineering Platform. He obtained his PhD (Chemical Engineering) from Birmingham University UK in 2001, and Chartered Engineer from Engineering Council, UK in 2011.  Prof. Tey is active in research and has published more than 120 journal papers in ISI journals. Prof Tey, together with his collaborators has secured a total of 46 research grants worth more than RM20 million in the past 18 years. He is also the lead inventor for 10 patents being filled in Malaysia and the Patent Cooperation Treaty. He has successfully supervised 27 PhD, 23 MS thesis and more than 100 undergraduate dissertations to completion. Prof. Tey's research area can be broadly described as process development of biopharmaceutical production.  His group has successfully applying direct cell engineering approaches to manipulate apoptosis, and cell proliferation that resulted in substantial improvements in cell lines of biopharmaceutical importance. He is also interested in the production and purification of virus-like-particles (VLP), and has successfully developed several direct and fast purification methods to purify the recombinant VLPs from microbial cell lysate.  Prof Tey is the Subject Editor for Food and Bioproducts Processing journal and the founding chairman of IChemE’s Biochemical Engineering Special Interest Group (BESIG) in Malaysia.

Academic degrees

  • Doctor of Philosophy in Chemical Engineering, University of Birmingham, UK, 2000
  • Degree in Biotechnology, Universiti Pertanian Malaysia, 1994

Professional affiliations

Member of International Professional Bodies

  • Institute of Chemical Engineers (IChemE), Chartered Engineer

Research Interests

Smart or stimuli-responsive polymers and hydrogels undergo abrupt changes in volume and structure in response to environmental changes, such as pH, temperature, electric field, antigen/antibody etc. Our current research focuses are utilizing these fascinating properties of stimuli-responsive hydrogels and polymers for various biomedical applications such as smart biosensor systems, targeted drug delivery and protein separation. The critical challenges of biosensor development are reduction in detection time, minimizing sensor size, simplifying fabrication, and developing more accurate and reliable protocol. Antigen-antibody stimuli-responsive hydrogels can be used as biosensor platform to detect antigen/antibody. An ideal protein drug delivery system should have controlled-release of the encapsulated drug at the targeted site of action and protect them from proteolytic degradation and acid hydrolysis. pH stimuli-responsive hydrogels can be used to design an oral protein drug delivery system. In addition, the pH and temperature responsiveness of the smart polymer can be used as salt and solvent free environmentally friendly chromatographic matrix media for protein purification

Research Projects

  • Bioseparation
  • Smart material for bioseparation and drug delivery
  • Microencapsulation for food engineering

Education

Units taught

CHE2871 - Biochemistry for Engineers

CHE3171 - Bioprocess Technology

No content

Local grants

  • An investigation of global limiting factors in fermentation process for recombinant protein production in periplasm of Escherichia coli, Tey Beng Ti, Ooi Chien Wei, Ramanan Nagasundara, 2016-2019, FRGS, RM107,000

Current supervision

Christian Michel Bongard

Functionalization of glove wears with advanced polymer techniques

2016-present

Monash University Malaysia

Completed supervision

Ng Hon Wei

Polymer modified ion exchange adsorbent for the flow-through chromatography of hepatitis B virus-like particle

2018

Monash University Malaysia

Lim Swee Lu

Development of hydrogel based biosensor for the detection of anti HBcAg antibody

2017

Monash University Malaysia

Local Award/Recognition/Exhibition/Stewardship

  • National Outstanding Educator Award (Research category) - Educoop, 2017
  • ITEX (Gold): Hydrogel-Based Biosensor for Point-of-Care Diagnosis of Hepatitis B Infection -  ITEX, 2018