Dr Mohd Farooq Shaikh

Senior Lecturer

Jeffrey Cheah School of Medicine & Health Sciences

Email: farooq.shaikh@monash.edu
Tel: +603 5514 4483
Office: Room 3-2-09

ORCID ID: https://orcid.org/0000-0001-9865-6224

Profile Summary

Dr Mohd Farooq Shaikh is Senior Lecturer at Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia. He is actively involved in neuropharmacological research. His personal interest is experimental epilepsy and the discovery of anti-epileptic drugs from diverse sources including medicinal plants. His research applies multifaceted approach using in-silico, in-vitro and in-vivo techniques. Currently, his team is working on epilepsy and Alzheimer’s disease related cognitive dysfunctions and won various national awards for innovation in research. He is a recipient of Monash's PVC award for Excellence in Research and Malaysian Society of Neuroscience (MSN)-best publication award in 2017. He is involved in PhD supervision and publishing papers in high impact journals.

Dr Farooq completed his PhD in Pharmacology from the Institute of Chemical Technology, University of Mumbai, India, in 2012. During his PhD (2011), he was also selected by the International Brain Research Organization (IBRO) to be part of the prestigious Young Scientist Training Program for his research work in epilepsy. In 2012, he was awarded the IBRO-APRC fellowship to continue his post-doctoral studies at School of Biomedical Sciences, University of Queensland, Australia, where he worked with Dr Karin Borges on epilepsy therapy research.

Qualifications

  • Graduate Certificate in Higher Education (GCHE), Monash University, Malaysia.
  • PhD in Pharmacology, Institute of Chemical Technology, University of Mumbai, India.
  • MPharm in Pharmacology, Rajiv Gandhi University of Health Sciences, India.
  • BPharm, Rajiv Gandhi University of Health Sciences, India.

Professional Experience

2018 – Present Senior Lecturer, Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia.

2019 – Present Adjunct Senior Research Fellow, Department of Neuroscience, Central Clinical School, Faculty of Medicine Nursing and Health Sciences, Monash University, Australia.

2013 – 2017 Lecturer, Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia.

2012 IBRO-APRC Fellow, Department of Pharmacology, University of Queensland, Brisbane, Australia

2008 – 2012 PhD Student (Senior Research Fellow, Indian Council of Medical Research-2010-2012), Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, University of Mumbai, India.

2008 – 2012 PhD Student (Senior Research Fellow, University Grants Commission- MANF, India-2009), Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology,  University of Mumbai, India.

2007– 2008 Research Assistant, Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, University of Mumbai, India.

Leadership and Coordination

  • Leading Neuropharmacology Research Cluster at Jeffrey Cheah School of Medicine and Health Sceinces, Monash University Malaysia since 2014.
  • Regional Representative for Young Epilepsy Section-International League Against Epilepsy (YES-ILAE) to promote epilepsy research and support young epileptologist and basic epilepsy researcher in their career path.
  • Deputy Chair, Monash University Malaysia- Animal Ethics Committee (MUM-AEC).
  • Ex-co Member of Malaysian Epilepsy Society
  • Ex-co Member of Malaysian Society of Pharmacology & Physiology (MSPP).
  • Coordinator- Pharmacology for MBBS program at Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia.
  • Coordinator  for zone ‘M’ for “Malaysian Brain Bee Challenge” a nationwide Univeristy-Community project to find Malaysian Brain Bee who will represent Malaysia in International Brain Bee Challenge every year.
  • Coordinator for zone ‘M’ for “Malaysian Brain Bee Challenge-Junior” a national level Univeristy-Community project for student aged 10-12 years.
  • Organiser for “CURE: Epilepsy Seminar and Research Meeting”, selected to host 2018 Frontiers in Research Seminar Series Program funded by CURE (Citizens United for Research in Epilepsy), USA to represent epilepsy research in University seminars and to educate and inspire the best and brightest minds to consider entering the field.

Research Interests

Neuropharmacology, Epilepsy, Alzheimer's disease and Cognition

Teaching Commitment

Unit MED 1011, MED 1022, MED 2031 and MED 2042.

Recent Publications

In Peer-Reviewed Indexed Journals

Kumari, Y., Choo, B.K., Shaikh, M.F., & Othman, I. (2019). Melatonin receptor agonist Piper betle L. ameliorates dexamethasone‑induced early life stress in adult zebrafish. Experimental and Therapeutic Medicine, 18, 1407-1416. https://doi.org/10.3892/etm.2019.7685. (Q4, IF: 1.448)

Paudel, Y. N., Angelopoulou, E., Piperi, C., Balasubramaniam, V. R., Othman, I., & Shaikh, M. F. (2019). Enlightening the role of high mobility group box 1 (HMGB1) in inflammation: Updates on receptor signalling. European journal of pharmacology, 172487. (Q2, IF: 3.170)

Saatheeyavaane Bhuvanendran, Nur Aziah Hanapi, Nafees Ahmed, Iekhsan Othman, Siti Rafidah Yusof, Mohd. Farooq Shaikh. (2019) Embelin, a potent molecule for Alzheimer’s disease: A proof of concept from BBB permeability, AChE inhibition and molecular docking studies. Frontiers in Pharmacology. (Accepted) (Q1, IF: 3.831).

Kundap, U. P., Paudel, Y. N., Kumari, Y., Othman, I. B., & Shaikh, M. F. (2019). Embelin prevents seizure and associated cognitive impairments in a pentylenetetrazole-induced kindling zebrafish model. Frontiers in Pharmacology, 10, 315. (Q1, IF: 3.831)

Choo, B., Kumari, Y., Hue, S. M. and Shaikh, M. F. (2019) “The treatment of epileptic seizures: the potential of Malaysian medicinal plants”, Neuroscience Research Notes, 1(3), pp. 35-53. doi: 10.31117/neuroscirn.v1i3.27.

Meng, B. C. K., Kundap, U. P., bin Johan Arief, M. F., Kumari, Y., Ling, Y. J., Piau, W. C., I. Othman & Shaikh, M. F. (2019). Effect of newer anti-epileptic drugs (AEDs) on the cognitive status in pentylenetetrazol induced seizures in a zebrafish model. Prog Neuropsychopharmacol Biol Psychiatry. 2019 Mar 4;92:483-493. doi: 10.1016/j.pnpbp.2019.02.014 (Q1, IF: 4.185)

Ayanabha Chakraborti, Mohd. Farooq Shaikh, Annamaria Vezzani, Jafri Malin Abdullah. Experimental models of epilepsy and related comorbidities. Front. Pharmacol. | doi: 10.3389/fphar.2019.00179. (2019) (Q1, IF: 3.831)

Paudel, Y. N., Semple, B. D., Jones, N. C., Othman, I., & Shaikh, M. F. (2019). High mobility group box 1 (HMGB 1) as a novel frontier in epileptogenesis: from pathogenesis to therapeutic approaches. Journal of Neurochemistry. https://doi.org/10.1111/jnc.14663. (Q1, IF: 4.609)

Amalina Ahmad Azam, Intan Safinar Ismail, Mohd Farooq Shaikh, Khozirah Shaari and Faridah Abas. Effects of Clinacanthus nutans leaf extract on lipopolysaccharide -induced neuroinflammation in rats: A behavioral and 1H NMR-based metabolomics study. Avicenna Journal of Phytomedicine, 2019, 273, 9 (2), 164-186. DOI: 10.22038/AJP.2018.11787

Alina Arulsamy, Yogini S Jaiswal, Bey Hing Goh, Saatheeyavaane Bhuvanendran, Thaarvena Retinasamy, Yatinesh Kumari, Iekhsan Othman, Leonard L Williams, Mohd. Farooq Shaikh. Neuroactive drugs–A perspective on drugs of synthetic and medicinal plants origin. Pharm Pharmacol Int J. 2018;6(6):422‒430.

Paudel, Y., Lisgaras, C., Lim, K. S. and Shaikh, M. F. “Epilepsy and Comorbidities: Towards unraveling the common underlying mechanisms”, Neuroscience Research Notes, 1(3), pp. 1-4. doi: 10.31117/neuroscirn.v1i3.20. (2018)

Yam N. Paudel, Mohd. Farooq Shaikh, Ángel Aledo Serrano, Yatinesh Kumari, Katina Aleksovska, Marina K. Alvim, Ayanabha Chakraborti, and Iekhsan B. Othman. HMGB1: A Common Biomarker and Potential Target for TBI, Neuroinflammation, Epilepsy and Cognitive Dysfunction. Frontiers in Neuroscience (2018). (Q1, 3.88)

Paudel, Y. N., Farooq Shaikh, M., Shah, S., Kumari, Y., Othman, I., Role of inflammation in epilepsy and neurobehavioral comorbidities: Implication for therapy. European Journal of Pharmacology (2018). (Q2, 3.01)

Muhammad Faiz Johan Arief, Brandon Kar Meng Choo, Jia Ling Yap, Yatinesh Kumari, Mohd Farooq Shaikh. A Systematic Review on Non-Mammalian Models in Epilepsy Research. Front. Pharmacol. doi: 10.3389/fphar.2018.00655 (2018). (Q1, IF: 4.4)

Saatheeyavaane Bhuvanendran, Yatinesh Kumari, Iekhsan Bin Othman, Mohd. Farooq Shaikh. Amelioration of cognitive deficit by embelin in a scopolamine-induced Alzheimer’s disease-like condition in a rat model. Front. Pharmacol. doi: 10.3389/fphar.2018.00665 (2018). (Q1, IF: 4.4)

Lin Lin Lee, V.; Kar Meng Choo, B.; Chung, Y.-S.; P. Kundap, U.; Kumari, Y.; Shaikh, M.F. Treatment, Therapy and Management of Metabolic Epilepsy: A Systematic Review. Int. J. Mol. Sci. 2018, 19, 871.. (2018). (Q2, IF: 3.2)

Choo BKM, Kundap UP, Kumari Y, Hue S-M, Othman I and Shaikh MF. Orthosiphon stamineus Leaf Extract Affects TNF-α and Seizures in a Zebrafish Model. Front. Pharmacol. 9:139. doi: 10.3389/fphar.2018.00139. (2018) (Q1, IF: 4.4)

Uday P. Kundap, Yatinesh Kumari, Iekhsan Othman, Mohd. Farooq Shaikh.  Zebrafish as a model for epilepsy-induced cognitive dysfunction: a pharmacological, biochemical and behavioral approach. Frontiers in Pharmacology. 8(515), doi: 10.3389/fphar.2017.00515. (2017) (Q1, IF: 4.4)

Kundap, U.P., Bhuvanendran, S., Kumari, Y., Othman, I. and Shaikh, M.F. Plant-derived phytocompound, Embelin in CNS disorders: A systematic review. Frontiers in Pharmacology, 8, p.76. (2017) (Q1, IF: 4.4)

Kundap, U., Jaiswal, Y., Sarawade, R., Williams, L. and Shaikh, M.F. Effect of Pelargonidin isolated from Ficus benghalensis L. on phenotypic changes in zebrafish (Danio rerio) embryos. Saudi Pharmaceutical Journal, 25(2), 249-257. (2017) (IF: 2.6)

Sayyad, M., Ning, T., Kumari, Y., Hing, G.B., Jaiswal, Y., Rosli, R., Williams, L. and Shaikh, M.F. Acute toxicity profiling of the ethyl acetate fraction of Swietenia macrophylla seeds and in-vitro neuroprotection studies. Saudi Pharmaceutical Journal, 25(2), 196-205. (2017) (IF: 2.6)

Jing Ying Hoo, Yatinesh Kumari, Mohd Farooq Shaikh, Seow Mun Hue, and Bey Hing Goh, “Zebrafish: A Versatile Animal Model for Fertility Research,” BioMed Research International, vol. 2016, Article ID 9732780, 20 pages, 2016. doi:10.1155/2016/9732780 (2016). (IF: 2.4)

Arulsamy A, Kumari Y, Shaikh MF. Reverse Pharmacology: Fast Track Path of Drug Discovery. Pharm Pharmacol Int J 4(3): 00077 (2016).

A Arulsamy, MF Shaikh. Impact of epilepsy on the manifestations of anxiety disorders. International Journal of Nutrition, Pharmacology, Neurological Diseases 6:3-11, (2016).

Qiang Ying Tan, Uday P Kundap, Yatinesh Kumari, Mohd. Farooq Shaikh, A Review on Natural Therapy for Seizure Disorders. Pharm Pharmacol Int J, 3(2): 00051 (2015).

A Arulsamy, BH Goh, MF Shaikh. Current status of epilepsy in Malaysia and way ahead. Int J Pharm Pharm Sci, Vol 7, Issue 1, 2-5 (2015).

J Sancheti, MF Shaikh, R Chaudhari, G Somani, S Patil, P Jain, S Sathaye. Characterization of anticonvulsant and antiepileptogenic potential of thymol in various experimental models. Naunyn-Schmiedeberg's Archives of Pharmacology, 1-8. (2014) (IF: 2.6)

Mateen Sayyed, MFShaikh, Aziz-ur-Raheman1, Jabeen, Syed YH. Pathophysiological and therapeutic approaches of cachexia: A silent & progressive killer accompanied by cancer. Int J Adv Pharmacy Med Bioallied Sci. 2, 1, (2014).

J Sancheti1, MF Shaikh, M Akhade, FA Shaikh, S Sathaye. Nutritional therapy for epilepsy. Journal of Pharmaceutical and BioSciences 1(4), 149-156 (2013).

J Sancheti, MF Shaikh, PF Khatwani, SR Kulkarni, S Sathaye. Development and validation of an HPTLC method for simultaneous estimation of L-glutamic acid and γ-aminobutyric acid in mice brain. Indian Journal of Pharmaceutical Sciences, 75(6), 716-721 (2013). (IF: 0.8)

MF Shaikh, KN Tan, K Borges. Anticonvulsant screening of luteolin in four mouse seizure models. Neuroscience Letters 55, 195-199, (2013). (IF: 2.1)

MF Shaikh, J Sancheti, S Sathaye. Effect of Eclipta alba on acute seizure models: a GABAA-mediated effect. Indian Journal of Pharmaceutical Sciences, 75(3), 380-384 (2013). (IF: 0.8)

Book /Book Chapters

Book Chapter: Brandon Kar Meng Choo and Mohd. Farooq Shaikh (May 30th, 2018). Zebrafish Model of Cognitive Dysfunction, Recent Advances in Zebrafish Researches Yusuf Bozkurt, IntechOpen, DOI: null. Available from: https://www.intechopen.com/books/recent-advances-in-zebrafish-researches/zebrafish-model-of-cognitive-dysfunction

Book Chapter: Divya Suares, Mohd. Farooq Shaikh, Clara Fernandes (2018), Nanotechnological Approaches For Management Of NeuroAIDS. Apple Academic Press, Inc., USA. (In press).

Book Chapter: MF Shaikh, LL Williams (2018), Hypertension: Pharmacology of Antihypertensives. Recent Progress in Medicinal Plants: Metabolic disorders. Vol. 48. Studium Press LLC, Houston, USA. (In press).

Book Chapter: MF Shaikh, LL Williams (2018), Hyperlipidemia: Pharmacology of Antihyperlipidemics. Recent Progress in Medicinal Plants: Metabolic disorders. Vol. 47. Studium Press LLC, Houston, USA. (In press).

Abstracts

Mohd. Farooq Shaikh, Uday Kundap, Yatinesh Kumari. (2018). Pharmacological model development for chronic epilepsy-induced cognitive Dysfunction in zebrafish. Abstract book. 32nd Scientific Meeting of Malaysian Society of Pharmacology and Physiology, 2018, Hotel Bangi, Putrajaya, 8-9 August 2018.

Development of Chronic Model of Epilepsy induced Cognitive Dysfunction in Zebrafish (2018). Abstract Book. 17th Asian and Oceanian Myology Centre (AOMC) Annual Scientific Meeting & 28th Malaysian Society of Neurosciences (MSN) Annual Scientific Meeting, 2018, Hotel Istana, KL, 28-29 July 2018.

U P Kundap, Y Kumari, I Othman, M F Shaikh. (2017). Effect of embelin in chronic epilepsy induced cognitive dysfunction in three-axis maze model of adult zebrafish. Epilepsia, 58(Suppl. 5): S5–S199. DOI: 10.1111/epi.13944.

Uday P Kundap, Yatinesh Kumari, Iekhsan Othman, Mohd. Farooq Shaikh. Embelin, a potential molecule to ameliorate seizure induced cognitive decline in a T-maze zebrafish model. European Neuropsychopharmacology, 2016, 26, S273-S274. DOI: 10.1016/S0924-977X(16)31159-2.

Kundap UP, Bhuvanendran S, Kumari Y and Shaikh MF (2016). Development of a zebrafish model for epilepsy and antiepileptic drugs induced cognitive dysfunction. Front. Cell. Neurosci. Conference Abstract: 14th Meeting of the Asian-Pacific Society for Neurochemistry. doi: 10.3389/conf.fncel.2016.36.00169.

Bhuvanendran S, Kumari Y, Othman I and Shaikh MF (2016). Memory enhancing effect of embelin against scopolamine-induced amnesia in Sprague Dawley rats. Front. Cell. Neurosci. Conference Abstract: 14th Meeting of the Asian-Pacific Society for Neurochemistry. doi: 10.3389/conf.fncel.2016.36.00164.

Retinasamy T, Kumari Y, Othman I and Shaikh MF (2016). Orthosiphon stamineus improves disturbances of learning, recognition memory and spatial long-term memory in scopolamine-induced amnesia in rats. Front. Cell. Neurosci. Conference Abstract: 14th Meeting of the Asian-Pacific Society for Neurochemistry. doi: 10.3389/conf.fncel.2016.36.00189.

Mohd. Farooq Shaikh, Zurina Hassan, Yatinesh Kumari, Amin Malik Shah A M, Iekshan Othman. Orthosiphon Stamineus Improve Memory and Hippocampal Long-Term Potentiation Impairment in a Chronic Cerebral Hypoperfusion Model in Rat. Cerebrovascular Diseases 42(suppl 1):152 · July 2016. DOI: 10.1159/000447732.

Uday P Kundap, Yatinesh Kumari, Iekhsan Othman, Nafees Ahmed, Mohd. Farooq Shaikh. Embelin's affinity towards the GABAA receptor and the ability to modulate neurotransmitters makes it an anticonvulsant compound. 20th Thai Neurosciences Society International Conference, July 2016, at Naresuan University Phitsanulok, Thailand.

Mohd. Farooq Shaikh, Discovery of Anticonvulsants using Reverse Pharmacology: A Fast Track Pathway” is delivered at the 1st International Conference Of Pharmacy And Health Sciences 2016 18th – 20th March 2016, Hotel Casuarina, Meru, Ipoh, Malaysia.

Uday P Kundap, Tiang Ning, Yatinesh Kumari, Iekhsan Othman, Mohd. Farooq Shaikh. Cognitive Dysfunctioning By Epilepsy & AEDs In Zebrafish Model. Malaysia Zebrafish Disease Models held at Cancer Research Malaysia, SJMC, Malaysia, 11-12 Nov. 2015.

Tharveena Retinasamy, Saatheeyavaane Bhuvanendran, Mohd. Farooq Shaikh, Yatinesh Kumari, Iekshan Othman, Goh Bey Hing, Amin Malik Shah A M, Aman Shah A M, Zurina Hassan. The Effect of Ethanolic Orthosiphon stamineus Extract on Learning & Memory in Chronic Cerebral Hypoperfusion Induced Cognitive Impairment in Rats. CDR Mini-Symposium on Drug Addiction and Neurodegeneration held from the 4th - 6th November 2015 at Auditorium Ishak Pateh Akhir, Sains, USM, Bukit Jambul, Penang.

Saatheeyavaane Bhuvanendran, Tharveena Retinasamy, Mohd. Farooq Shaikh, Yatinesh Kumari, Iekshan Othman, Zurina Hassan. Pharmacological evaluation of phytocompound Embelin, derived from Embelia ribes in Alzheimer’s disease using chronic cerebral hypoperfusion rats. CDR Mini-Symposium on Drug Addiction and Neurodegeneration to be held from the 4th - 6th November 2015 at Auditorium Ishak Pateh Akhir, Sains, USM, Bukit Jambul, Penang.

MF Shaikh, Iekhsan Othman. Neuroproteomics: A Guiding Light for Neurodegenerative Diseases’ Therapy”. CDR Mini-Symposium on Drug Addiction and Neurodegeneration to be held from the 4th - 6th November 2015 at Auditorium Ishak Pateh Akhir, Sains, USM, Bukit Jambul, Penang.

Y Kumari, BH Goh, MF Shaikh. Piper betel,a novel melatonin agonist for the treatment of sleep disorder. International Conference on Biomedical & Health Sciences Research 2015, Putrajaya, Malaysia (25-27 January 2015).

Research Grants

  • Tropical Biology and Medicine (TMB) Grant (2019), the project entitled " Therapeutic Potential of Curcumin Derivatives in Epileptic Seizures using Zebrafish as a Disease Model”. (Role: Principal Investigator, RM 8,000)Global Asia in the 21st Century (GA21) Large Grant (2018-2020) entitled “National Key Economic Plant ‘Orthosiphon Stamineus’ Leaf for the Treatment of Epilepsy”. (Role: Principal Investigator, RM 25,350)
  • Global Asia in the 21st Century (GA21) Large Grant (2018-2020) entitled “Potent Neuroprotective Proteins Derived from Malayan Snake Venom in Alzheimer’s Disease”. (Role: Co-investigator, RM 29,310)
  • Global Asia in the 21st Century (GA21) Seed Grant (2018-2019) entitled “Investigation of the anticonvulsive effect of the venom from Malaysian pit vipers; Calloselasma rhodostoma (Malayan pit viper) and Cryptelytrops purpureomaculatus (Mangrove pit viper) using in-vivo zebrafish model”. (Role: Co-investigator, RM 10,000)
  • PVC Award 2018 for Excellence in Research – Early Career Category (2018-2019). Research Grant (Role: Principal Investigator, RM 20,000)
  • Star Goose Sdn Bhd-Industrial Grant entitled (2018-2019) "Evaluation of the anticonvulsant potential of Goose bone in an experimental model of epilepsy". (Role: Principal Investigator, RM 20,000)
  • Tropical Biology and Medicine (TMB) Grant (2017-2018), the project entitled "Effect of Third Generation Anti-Epileptic Drugs (AEDs) On The Cognitive Status In An Epileptic Zebrafish Model”. (Role: Principal Investigator, RM 15,000)
  • FRGS (Fundamental Research Grant Scheme) (2016-2019), a project entitled "The role of the mGlu5-PKC epsilon-ERK1/2 molecular pathway in rat basolateral and central amygdalar glutamatergic hyperexcitability during ethanol withdrawal-induced anxiety". (Role: Co-investigator, RM 96,000)
  • MOSTI (Ministry of Science, Technology and Innovation, Malaysia) eScience Research Fund (2014-2017), a project entitled “Embelin, a Malaysian plant derived benzoquinone in the treatment of epilepsy induced cognitive dysfunction”. (Role: Principal Investigator, RM 166,000)
  • NKEA Research Grant Scheme (NRGS) Ministry of Agriculture And Agro-Based Industry, Malaysia (2014-2017), the project entitled “Evaluations of neuroprotective activity of standardized ethanolic Orthosiphon stamineus extract ameliorate cognitive alterations in Alzheimer’s disease”. (Role: Co-investigator,  RM 420,000)
  • NKEA Research Grant Scheme (NRGS) Ministry of Agriculture And Agro-Based Industry, Malaysia (2014-2017), the project entitled “Elucidating the anti-neuroinflammatory effect of Clinacanthus nutans on Lipopolysaccharide-induced neurotoxicity in BV2 cells and rat”. (Role: Co-investigator,  RM 400,000)
  • ECR seed grant 2014, MONASH University Malaysia, the project entitled “Evaluations of neuroprotective activity of standardized ethanolic Orthosiphon stamineus extract ameliorate cognitive alterations in Alzheimer’s disease”. (Role: Principal Investigator,  RM 30,000)

Research Student Supervision

Current

  1. Chung Yin-Sir Alexis (Main Supervisor) - PhD

    Investigation on Orthosiphon stamineus Benth Proteins in Central Nervous System

  2. Yam Nath Paudel (Main Supervisor) - PhD

    Investigation of plausible role of HMGB1 in chronic epilepsy-related cognitive dysfunction in zebrafish

  3. Vanessa Lin Lin Lee (Main Supervisor) - PhD

    Role of Malaysian Ikan Haruan (Channa striatus) Extract in Neuroinflammation-Mediated Epilepsy

  4. Brandon Choo Kar Meng (Main Supervisor) - PhD

    Effect of Newer Anti-Epileptic Drugs (AEDs) on the Cognitive Status in Pentylenetetrazol Induced Seizures in A Zebrafish Model

  5. Seyedah Taher Mirani (Main Supervisor) - PhD

    Mechanism of the long noncoding RNA SNHG18 in downregulating Sema5A expression in

    human glioblastomas

  6. Hui Xian Fong (Co-Supervisor) - PhD

    Executive Functioning Among Children with Autism Spectrum Disorder in Malaysia: A Developmental Perspective

  7. Atiqah Haizum Abdullah (Co-Supervisor) - PhD

    Discovery of Biological Active Molecule from Malayan Snake Venom for

    Neurodegenerative Disease

  8. Mohammad Borhan Uddin (Co-Supervisor) - PhD

    Evaluation of inorganic nano-crystals as potential tools for delivery of siRNA targeting ion channels and transporters in breast cancer cells

  9. Farah Rehan (Co-Supervisor) - PhD

    Formulation of Casein Nanomicelles as a Novel Anticancer Drug Delivery System

  10. Amalina Azam (UPM) (External Co-Supervisor) - PhD

    Elucidating the anti-neuroinflammatory effect of Clinacanthus nutans on Lipopolysaccharide (LPS)-induced neurotoxicity in BV2 cells and rat.

  11. Shantini a/p Vijayabalan (Taylor’s University) (External Co-Supervisor) - PhD

    Effects of Curcumin and Piperine on the Degeneration of Β-amyloid Proteins In Streptozotocin-induced Alzheimer Disease-like Condition In Sprague Dawley Rats

  12. Atif Usman (Co-Supervisor) - PhD

    Cardiovascular Complications in Diabetic Ketoacidosis: Clinical and Experimental Approach for Improved Diagnosis and Management

  13. Haziq Aiman(UKM) (External Co-Supervisor) - Master

    Involvement of Mammalian Target of Rapamycin Complex 2 (Mtorc2) And Protein Kinase C Epsilon (Pkcε) In Ethanol Withdrawal-induced Anxiety

  14. Yiew Jin (Co-Supervisor) – B. Sci. (Honours)
    Snake venom protein as a therapeutic strategy for epilepsy and memory

Completed

  1. Uday P. Kundap (Main Supervisor) – PhD (2019)

    Pharmacological Evaluation of Embelin in Epilepsy Induced Cognitive Impairment in Zebrafish

  2. B. Saatheeyavaane Pillai (Main Supervisor) – PhD (2019)

    Neuroprotective Effect of Embelin in Experimental Models of Alzheimer's Disease

  3. Thaarvena Retinasamy (Main Supervisor) – PhD (2019)

    Evaluation of Neuroprotective Activity of Standardized Ethanolic Orthosiphon stamineus Extract to Ameliorate Cognitive Alterations in Alzheimer's Disease

  4. Qian Ying Tan (Main Supervisor) – B. Med. Sci. (Honours) (2019)

    Impact of Epilepsy on Gut Microbiota and Possible Therapeutics

  5. Sabrina Ooi Xu Peng (Co-Supervisor) – B. Sci. (Honours) (2019)

    Impact of Sleep Deprivation on Neurobehavioral Parameters in a Zebrafish Model

  6. Yanning Yong (Co-Supervisor) – B. Sci. (Honours) (2019)

    Cell-based and zebrafish (Danio rerio) phenotypic investigation of cytotoxic properties in Arctium lappa L. root extract

  7. Qi En Goh (Co-Supervisor) – PGDip. BioMed Sci. (2018)

    The Identification and Partial Purification of Acetylcholinesterase (Ache) in Naja sumatrana and Ophiophagus hannah Venom

  8. Brandon Choo Kar Meng (Co-Supervisor) – B. Sci. (Honours) (2017)

    Evaluation of anti-convulsant potential of Orthosiphon stamineus in zebrafish

  9. Jing Ying (Co-Supervisor) – B. Sci. (Honours) (2015)

    Effect of medicinal plant in experimental model of infertility

  10. Alina Arulsamy (Co-Supervisor) – B. Sci. (Honours) (2014)
    Pharmacological Evaluation of Leucaena leucocephala in Anxiety and Depression

Awards and Fellowships

  • “Young Researcher Award 2019” by Malaysian Society of Pharmacology and Physiology (MSPP), during 33rd Annual Meeting of MSPP at Everly Hotel, Putrajaya, Malaysia on 15-16 July 2019.*
  • “Young Teachers Award 2019” for Pharmacology category by Malaysian Society of Pharmacology and Physiology (MSPP), during 33rd Annual Meeting of MSPP at Everly Hotel, Putrajaya, Malaysia on 15-16 July 2019.
  • Pro-Vice Chancellor’s (PVC) Award 2018 for Excellence in Research – Early Career Category by Monash University Malaysia
  • Malaysian Society of Neurosciences (MSN) 2018 Best Publication Award for the paper entitled “Zebrafish as a Model for Epilepsy-Induced Cognitive Dysfunction: A Pharmacological, Biochemical and Behavioral Approach”.
  • Best Poster Award at Monash Medicine Curriculum Conference 2018 for the project “Innovative Approach to Enhance Medical Students’ Learning of Basic Immunology Concepts”.
  • Silver Medal at ITEX 2018
  • Bronze Medal at PECIPTA 2017
  • IBRO-APRC Exchange Fellowship-2012, to work at the University of Queensland, Brisbane, Australia (Only 3 scientists from Asia-pacific region are selected every year by the International Brain Research Organization (IBRO) for this prestigious program). (Role: Visiting Academic, USD 8500)
  • Fellow-Young Investigator Program (YIP) -2011, selected by the International Brain Research Organization (IBRO) to undergo training in the European laboratory-Milano, Italy, 2011. (Only 75 scientists from laboratories all over the world were selected for this prestigious program).
  • International Brain Research Organization (IBRO) Travel Fellowship to participate and present a paper at 8th World Congress of Neuroscience, Florence, 2011.
  • Senior Research Fellowship, Indian Council of Medical Research, India, 2010.
  • Senior Research Fellowship, University Grants Commission- MANF, India 2009.
  • Research Scholarship, Dr. Palep’s Medical Research Foundation, India, 2008.

Innovation and Patents

  • Participated and won a SILVER medal at annual ITEX 2018, an exhibition aimed to cultivate the ability to think critically - a quality separating innovators from followers, for the project entitled “Lanctos 75TM for Mental Wellness”.
  • Participated and won a BRONZE medal at PECIPTA 2017, an International Conference and Exposition on Inventions by Institutions of Higher Learning, Malaysia, for the project entitled “NP-A as A Memory Enhancer and Potential Molecule for Neurodegenerative Diseases”.
  • A patent entitled "A Pharmaceutical Composition for Treating a Sexual Dysfunction in Males and a Method for Producing Thereof" has been filed before Malaysia Intellectual Property Office (MyIPO). The details of the said patent application are as follows:
    Application No.     : PI 2017702515
    Applicant: Monash University Malaysia
    Filing Date: 10 July 2017
  • A patent entitled “Extract Of Orthosiphon Stamineus, Formulations, And Uses Thereof” will be filed by the end of Aug 2017 with industry partner Natureceuticals.

Professional Memberships

  • Regional Representative- Young Epilepsy Section-International League Against Epilepsy (YES-ILAE)
  • Member – International Brain Research Organization (IBRO)
  • Life Member – Malaysian Society of Neuroscience (MSN)
  • Ex-co and Life Member – Malaysian Society of Epilepsy
  • Member – Malaysian Society of Pharmacology & Physiology (MSPP)
  • International Member – American Epilepsy Society (AES)
  • Member – MONASH University Institute of Graduate Research (Level 2)
  • Member – ADI-Advisors, ADI Instruments Ltd.
  • Member- Registered Pharmacist, Maharashtra State Pharmacy Council (MSPC)
  • Topic Editor: Frontiers in Pharmacology, Frontiers in Neurology and Frontiers in Neuroscience
  • Topic Editor: Neuroscience Research Notes
  • Editorial Board Member: International Journal of Pharmacy and Pharmaceutical Sciences (IJPPS),  International Journal of Advances in Pharmacy, Medicine and Bioallied Sciences (Int J Adv Pharm MED Bioallied Sci), Pharmacy & Pharmacology International Journal, Research in Pharmacy and Health Sciences
  • Reviewer :
    • Neurobiology of Disease
    • Journal of Neurochemistry
    • ACS Chemical Neuroscience
    • Neuropharmacology
    • Frontiers in Pharmacology
    • ACS Molecular Pharmaceutics
    • Brain Sciences
    • Experimental Biology and Medicine
    • Journal of Neuroimmune Pharmacology
    • Journal of Psychiatric Research
    • Journal of Neuroinflammation
    • Phytotherapy Research
    • BMC Complementary and Alternative Medicine
    • International Journal of Molecular Sciences, mdpi
    • European Journal of Pharmaceutical Sciences
    • Biomedicine & Pharmacotherapy
    • Nutrients
    • Life Sciences
    • Brazilian Journal of Pharmaceutical Sciences
    • Journal of Medicinal Plant Research
    • Current Science
    • International Journal of Pharmacy and Pharmaceutical Sciences
    • Indian Journal of Pharmaceutical Education and Research

Certification

  • Certified Microsoft Innovative Educator (2016)
  • Foundation in Teaching (FIT), Monash University Malaysia (2015)
  • Laboratory Safety conducted by Department of Chemistry, ICT, Mumbai, India (Feb. 3-4, 2011)
  • Fire Safety, University of Queensland, Brisbane, Australia. (Aug. 2012)

Invited / Guest talks / Special lectures

2019

  • A guest lecture was delivered on “The Opportunity on Epilepsy Research” at the Symposium 'Toward the Next Generation of Epileptologists' at the Central Laboratory of Diponegoro National Hospital (RSND), Semarang, Indonesia on 15th July 2019.
  • Invited as a keynote speaker for the talk entitled “Small Fish, Big Impact: Zebrafish in Experimental Neurology” at SIPSAM 2019 (Semarang International Physiology Seminar and 28th Annual Meeting of Indonesian Physiology Society) at Semarang Indonesia 12-13 July 2019.
  • Invited speaker to talk on “Multifactorial Approach for A Multifactorial Condition: Modelling Alzheimer’s disease”. at SIPSAM 2019 (Semarang International Physiology Seminar and 28th Annual Meeting of Indonesian Physiology Society) at Semarang Indonesia 12-13 July 2019.
  • An invited talk on “Basic Science Epilepsy Research” was delivered at 29TH Annual Scientific Meeting Of The Malaysian Society Of Neurosciences, 4-8 July 2019.

2018

  • An invited talk on “Use of Zebrafish in Pre-Clinical Research" was delivered at AIKTC, School of Pharmacy, Mumbai, India on 18th September 2018.
  • An invited talk on “Modeling Alzheimer’s Disease: An in-vitro, in-vivo and in-silico approach” was delivered at 3rd Neuroscience Symposium organized by IIUM, Kuantan on 2nd May 2018.
  • An invited talk on “Research collaboration: opportunity & experience” was delivered at 3rd Neuroscience Symposium organized by IIUM, Kuantan on 2nd May 2018.

2017

  • An invited talk on “Epilepsy and Comorbidities Research in Monash” was delivered at MyNeuro 2017: Symposium on Epilepsy Research Cross Talk, held at Hotel Istana, Kuala Lumpur, 11-13 August 2017.

2016

  • An invited talk on “Discovery of Anticonvulsants using Reverse Pharmacology: A Fast Track Pathway” is delivered at the 1st International Conference Of Pharmacy And Health Sciences 2016 18th – 20th March 2016, Hotel Casuarina, Meru, Ipoh, Malaysia.

2015

  • An invited talk on “Natural therapy in epilepsy: Scope and challenges” is delivered at 26TH Annual Scientific Meeting Of The Malaysian Society Of Neurosciences (MSN 2015) 5th – 7th June 2015, WEIL Hotel, Ipoh, Malaysia.

2013

  • An IBRO special lecture on “Drug Discovery of Antiepileptics” is delivered at MONASH University Malaysia during IBRO Advanced School of Neuroscience organized by Brain Research Institute, Monash University Malaysia, on 9th September 2013.
  • A guest lecture on “Adult zebrafish: A better model for antiepileptic screening”  is delivered on 3rd December 2013 at Institute of Chemical Technology (ICT), Mumbai, India organized by Department of Pharmaceutical Sciences & Technology of ICT and supported by TEQIP.
  • A comprehensive discussion and a guest lecture on “Discovery of Centrally Acting Drugs: Anti-epileptics” is delivered during National Pharmacy Week Celebrations, 2013 at MESCO College of Pharmacy, Hyderabad, India on 26th November 2013.

Academic visits

  • Visiting Researcher, Department of Neuroscience, Central Clinicla School, The Alfred Hospital, Monash University, Melbourne, Australia. Feb. 2019 to June 2019.
  • Institute of Neurology, University College London,  London, UK, on  14th May 2018.
  • Research Centre for Neurosciences Mahidol University, Bangkok, Thailand. Basic Neuroscience Chapter- Malaysian Society of Neuroscience, Delegates’ visit, 19-21 November 2017.
  • Institute of Neurological Sciences Venice, Summer School Program at Venice International University, San Servolo, Venice; 16-29 July 2017.

Workshops / Training programmes attended

  • “Workshop on Intelligent Signal & Imaging for Biomedical Applications” 8th & 9th October 2015, The Gallery, Level 8, Le Meridien Hotel, Kuala Lumpur.
  • Training course on “How to use PowerLabs” at The ADInstruments South East Asia Training Center, Subang Jaya, Selangor Malaysia on 31st March 2015

Conferences / Symposiums attended

  • 33rd MSPP, The Everly Hotel, Putrajaya, Malaysia 15-16th July 2019.
  • Semarang International Physiology Seminar and 28th Annual Meeting of Indonesian Physiology Society (SIPSAM), Semarang, Indonesia, 13-14th July 2019.
  • 29th MSN Annual Scientific Meeting, Greant Riverview Hotel, Kota Bharu, Malaysia, 4-8th July 2019.
  • 33rd International Epilepsy Congress, at Bangkok Convention Center, Bangkok, Thailand, 22-26 June 2019.
  • 32nd MSPP 2018, Hotel Bangi, Putrajaya, 8-9 August 2018.
  • AOMC-MSN 2018, at Hotel Istana, Kuala Lumpur, 27-28 July 2018.
  • MyNeuro 2017 held at Hotel Istana, Kuala Lumpur, 11-13 August 2017.
  • BETT Asia Expo, 2016, Mandarin Oriental, Kuala Lumpur, Malaysia, 15 – 16 November 2016.
  • Asia Pacific Stroke Conference 2016, Brisbane Convention and Exhibition Centre, Brisbane, Qld, Australia, 14-17 July 2016.
  • 1st International Conference Of Pharmacy And Health Sciences 2016 18th – 20th March 2016, Hotel Casuarina, Meru, Ipoh, Malaysia
  • CDR Mini-Symposium on Drug Addiction and Neurodegeneration, USM Penang, 4-6th Nov. 2015.
  • Workshop on Intelligent Signal & Imaging for Biomedical Applications (WISIBA 2015) held on 8-9 October 2015 at Hotel Le Meridien, Kuala Lumpur, Malaysia.
  • 26TH Annual Scientific Meeting Of The Malaysian Society Of Neurosciences (MSN 2015) 5th – 7th June 2015, WEIL Hotel, Ipoh, Malaysia.
  • 4th NeuroMalaysia Symposium, Monash University Malaysia (September 28, 2013).