Director Tropical Medicine and Biology Multidisciplinary Platform
Professor Sadequr Rahman is the Director of the Tropical Medicine & Biology Multidisciplinary Platform, which the Genomics Facility share with two other clusters, Infection and Immunity and Telemedicine.
He is a professor of plant genetics and has worked with The Commonwealth Scientific and Industrial Research Organization’s (CSIRO) plant industry, Australia for 22 years before joining the Monash University in 2011. His core research interests focus on genes involved in the biosynthesis of novel lipids and polysaccharides in plants, and DNA based identification of avian species in the tropics. However, Prof Sadequr has been expanding his scope of interest in the era of Genomics to microbial and environmental metagenomics resulting in more than 90 published journal articles.
Director Genomics Facility
Dr. Qasim Ayub has recently joined Monash University Malaysia as Associate Professor and Head of the Genomics Facility. He trained as a clinician and subsequently obtained his doctorate from the University of North Texas, Denton, USA. In Pakistan he assisted in setting up a state of the art molecular biology research facility, the Biomedical and Genetic Engineering Laboratories, in Islamabad, that became the focal point for the Human Genome Diversity Project. Several of the novel male specific markers that were identified during his studies of the Pakistani populations are now routinely used in forensic DNA identification. For this work he was awarded the President of Pakistan’s Medal of Excellence for contributions to science in 2006.
From 2008 until August 2017 he worked at the world renowned Wellcome Trust Sanger Institute in Hinxton, near Cambridge, and was a member of the 1000 Genomes Project Consortiums and the gorilla sequencing team that published several high profile papers. His research focuses on human population and evolutionary genomics and over the past decade he has analyzed DNA variation in worldwide ethnic and linguistic groups in order to understand their origins and relatedness. He continues to maintain his interest in South Asian population genetics and high-altitude adaptation in the Himalayas. At Monash University Malaysia he is developing projects in evolutionary and disease genomics. The aim is to analyze DNA variations in humans and other species to ascertain their origins, migration patterns, and improve our understanding of genetic factors involved in the host pathogen interactions.
Assistant Lecturer, Bioinformatics
Dr Wee received his B.Sc. in Bioinformatics from Multimedia University (MMU) in 2012 and his Ph.D in Bioinformatics from University of Malaya where he continued to work as Post Doctoral Research Fellow under Centre for Research in Biotechnology for Agriculture (CEBAR). In 2017, he joined Monash as an Assistant Lecturer in the School of Science and engages in education and research through contribution to multidisciplinary research projects. He has a proven record in publication and published around 24 high impact papers since 2012. He has also taken part in setup, design, establishment and maintenance of new bioinformatics laboratory.Dr Wee has been involved in a variety of Next Generation Sequencing (NGS) projects such as whole genome and transcriptome analysis on eukaryotic genomes, bacteria genome and metagenomics. He is familiar with Bioinformatics analysis such as genome assembly, genome annotation, genes comparative study, identification of SNP variants and prediction on the effect of the SNP variants, differential gene expression analysis, pan-genome analysis, phylogenetic tree analysis, prophage identification. He also developed useful Bioinformatics tools and pipelines such as the Pairwise Genome Comparison (PGC) and the Pathogenomics Profiling Tool (PathoProT). PGC is a bioinformatics tool which allow user to perform pairwise genome alignment and visualize the alignment in a circular layout and PathoProT allow user to screen for virulence genes in the genome. These 2 tools have been implemented and integrated into few published database such as VibrioBase and HelicoBase.Dr Wee current research projects are the whole genome analysis of Mycobacterium cosmeticum and transcriptomic analysis of Bosenbergia rotunda.
Assistant Manager, Genomics
Yin Peng received her B.Sc. in Biotechnology and Molecular Bioscience from Rochester Institute of Technology, NY, USA under the JPA Scholarship in 2013. During her undergraduate study, she did her research under supervision of Dr. Irene Evans on yeast prion and assess the performance of new Targeted Molecular Imaging Agents (TMIAs) supplied at RIT by Hans Schmitthenner's laboratory using confocal microscopes. She assisted lecturers in handling lab activities in Genomics and Microbiology courses as teaching assistant. She worked in University Malaya as research assistant after she graduated before joining Genomics Facilities of Monash University Malaysia in December 2013.
Prior to this managerial role, she was the sole person responsible for most of the wet lab assignments from sample preparation, library preparation, quality control of samples and starting Miseq runs. Currently, she is assisting the directors in overseeing the lab operations, maintaining the PQMS of the facility, providing consultations to other researchers on NGS-related technical inquiries and establishing collaborations with both academic and industrial partners.
Research Associate, Genomics
She joined the team in July 2017 and is currently responsible for most of the wet lab assignments.
As a graduate from Monash Malaysia with BSc (Biotechnology), Wilhelm had grown fond of the work in Bioinformatics. With his interest, together with the support of the Genomics Facility, he had the opportunity to work with the team in 2015 and completed his 6-month internship as a Research Assistant, familiarizing with the pipelines used in the field of Genomics and Bioinformatics while applying all the relevant skills acquired throughout his academics years.
He has then joined the team as the administrator for management and operation of the lab while serving as a contact point for external liaison.