Dr. How Chee Wun
After completing his research fellowship in Spain and Taiwan, Dr How Chee Wun became a post-doctoral fellow specialised in drug delivery system. He is now a Lecturer in School of Pharmacy since 2019. With his qualifications in nanomedicine and pharmacology, his research interests focused on the delivery of medications and phytoceuticals using nanoparticles. Apart from applying his research experience in oncology, Dr How current research involved network pharmacology, exosomes, and biophysics. His works are interdisciplinary in nature. Dr How has guided numerous students in their studies. He was a consultant for a pharmaceutical company and authored a number of research publications.
- Doctor of Philosophy in Nanomedicine in Oncology, Universiti Putra Malaysia, 2014
- Bachelor of Science in Biomedical Science (Hons), Universiti Tunku Abdul Rahman, 2008
Sep 2016 - Feb 2018: Supervising Consultant Kabey Pharmaceutics
June 2019 - Current: Lecturer, School of Pharmacy, Monash University Malaysia
Dec 2018 - June 2019: Assistant Director for Centre for Pre-University Studies, MAHSA University
Sep 2016 - June 2019: Lecturer, Faculty of Pharmacy, MAHSA University
Jan 2015 - Aug 2016: Post-doctoral Fellow, Universiti Putra Malaysia
Awards and Honours
- MOVER Mundus Awards from European Union
Dr How Chee Wun research interest is interdisciplinary in nature. His expertise in drug delivery systems and formulation is integrated with pharmacokinetics, pharmacology, biophysics, stem cells, extracellular vesicles, and network pharmacology in various disease models like cancers and neurodegenerative diseases. Dr How currently has collaboration with Taylor’s University, UCSI, UPM, UKM, and several other industrial partners.
Scholarly Journals (Refereed Only)
KL Tan, WC Chia, CW How, YS Tor, PL Show, QHD Looi, JB Foo. (2021). Benchtop Isolation and Characterisation of Small Extracellular Vesicles from Human Mesenchymal Stem Cells. Molecular biotechnology, 1-12
CW How, YS Ong, SS Low, A Pandey, PL Show, JB Foo. (2021). How far have we explored fungi to fight cancer? Seminars in cancer biology.
FHZ Ansar, SY Latifah, WHBW Kamal, KC Khong, Y Ng, JN Foong, B Gopalsamy, WK Ng, CW How… (2020). Pharmacokinetics and Biodistribution of Thymoquinone-loaded Nanostructured Lipid Carrier After Oral and Intravenous Administration into Rats. 15: 7703.
Kai-Wen Lee, Chee Wun How, Lei Chen, Po Ting Chen, John Chi-Wei Lan, Hui-Suan Ng. (2019). Integrated extractive disruption of Gordonia terrae cells with direct recovery of carotenoids using alcohol/salt aqueous biphasic system. Separation and Purification Technology 223, 107-112
Chaw Yee Beh, Abdullah Rasedee, Gayathri Thevi Selvarajah, Latifah Saiful Yazan, Abdul Rahman Omar, Jia Ning Foong, Chee Wun How, Jhi Biau Foo. (2019). Enhanced anti-mammary gland cancer activities of tamoxifen-loaded erythropoietin-coated drug delivery system. PloS one 14 (7), e0219285
Noraini Nordin, Swee Keong Yeap, Heshu Sulaiman Rahman, Nur Rizi Zamberi, Nadiah Abu, Nurul Elyani Mohamad, Chee Wun How, Mas Jaffri Masarudin, Rasedee Abdullah, Noorjahan Banu Alitheen. (2019). In vitro cytotoxicity and anticancer effects of citral nanostructured lipid carrier on MDA MBA-231 human breast cancer cells. Scientific reports 9 (1), 1614
Jia Ning Foong, Gayathri Thevi Selvarajah, Abdullah Rasedee, Heshu Sulaiman Rahman, Chee Wun How, Chaw Yee Beh, Guan Young Teo, Chi Ling Ku. (2018). Zerumbone-Loaded Nanostructured Lipid Carrier Induces Apoptosis of Canine Mammary Adenocarcinoma Cells. BioMed Research International. 2018: Article ID 8691569
Yong Sze Ong, Latifah Saiful Yazan, Wei Keat Ng, Rasedee Abdullah, Noordin M Mustapha, Sarah Sapuan, Jhi Biau Foo, Yin Sim Tor, Chee Wun How, Napsiah Abd Rahman, Fatin Hannani Zakarial Ansar. (2018). Thymoquinone-loaded in nanostructured lipid carrier showed enhanced anti-cancer activity in 4T1 tumour-bearing mice. Nanomedicine. 13(13): 1567-1582.
Jhi Biau Foo, May Lee Low, Ji Hui Lim, Yan Zhi Lor, Rusyidah Zainol Abidin, Vilasini Eh Dam, Napsiah Abdul Rahman, Chaw Yee Beh, Lee Chin Chan, Chee Wun How, Yin Sim Tor, Latifah Saiful Yasan. (2018). Coppercomplex derived from S-benzyldithiocarbazate and 3-acetylcoumarin induced apoptosis in breast cancer cell. Biometals. 1-11.
Noraini Nordin, Yeap Swee Keong, Nur Rizi Zamberi, Nadiah Abu, Nurul Elyani Mohamad, Heshu Sulaiman Rahman, Chee Wun How, Mas Jaffri Masarudin, Abdullah Rasedee, Noorjahan Banu Alitheen. (2018). Characterisation and toxicity of citral incorporated with nanostructured lipid carrier. PeerJ. 6: e3916.
Chaw Yee Beh, Chee Wun How, Jhi Biau Foo, Jia Ning Foong, Gayathri Thevi Selvarajah, Rasedee Abdullah. (2017). Development of erythropoietin receptor-targeted drug delivery system against breast cancer using tamoxifen-loaded nanostructured lipid carriers. Drug Design, Development and Therapy. 2017(11): 771-782.
Peter Waziri, Rasedee Abdullah, Swee Keong Yeap, Abdul Rahman Omar, Nur Kartinee Kasim, Ibrahim Malami, Chee Wun How, Imaobong Etti, Mary Ladidi Abu. (2016). Clausenidin induces caspase-dependent apoptosis in colon cancer. BMC Complementary and Alternative Medicine. 16: 256-68.
Research Grants (Completed)
Type of Grant: MAHSA University Research Grant (RP89-0216)
Title of Research: Investigation of Anticancer Properties of Copper Complex Toward Breast Cancers: In Vitro Studies
Main Investigator: Dr Foo Jhi Biau
Co-Investigator: Dr How Chee Wun
Date/Duration: Sept 2016 - Mac 2018
Amount: RM 50,000
Type of Grant: Sciencefund (02-01-04-SF1210)
Title of Research: Enhancement of Cytotoxic Effects of Selective Oestrogen Receptor Modulators on Breast Cancer by Recombinant Human Erythropoietin
Main Investigator: Prof. Dr Rasedee Abdullah
Co-Investigator: Dr How Chee Wun, A/P Dr Latifah Saiful Yazan, Dr Zeenathul Nazariah Allaudin
Date/Duration: Oct 2013 - Mac 2016
Amount: RM 239,000
Postgraduate (MSc & PhD)
Mohd Asiful Islam (PhD: Completed - 2018)
Molecular Characterization And Validation Of Exome Variants In Primary Antiphospholipid Syndrome (APS) Patients
- Main Supervisor
Ahmad Aizat Aziz (PhD: Completed - 2018)
Exploration of SNPs, mRNA expression and protein levels of CYPIBI as predictive biomarkers in the treatment response of breast cancer patients undergoing adjuvant chemotherapy
Nurshazwani Binti Muhamad Sayuti (MSc: Completed - 2018)
Bioactivity- Guided Fractionation of Tiger Milk Mushroom Extract on Human Lungs Cell Line
Malaysian Association for Cancer Research