Dr. Yasodha Sivasothy

.

Lecturer
School of Pharmacy

yasodha.sivasothy@monash.edu
+603 5514 6356
Room  2-5-08

Dr. Yasodha Sivasothy graduated from Universiti Sains Malaysia with a BSc in Chemistry and a PhD in Natural Products Chemistry. Prior to joining Monash University Malaysia, she was a staff of University of Malaya, Taylor's University and Sunway University. Her research focuses primarily on the extraction, isolation and characterisation of bioactive secondary metabolites from the Malaysian flora.

Qualifications

- Doctor of Philosophy in Natural Products Chemistry, University Sains Malaysia, 2009

- Bachelor of Science in Chemistry (Hons), Universiti Sains Malaysia, 2002

Employment History

Jan 2020 - Current: Lecturer, School of Pharmacy, Monash University Malaysia

Aug 2018 - Dec 2019: Assistant Manager - Laboratory, Sunway University

Aug 2017- Dec 2017: Part-time Lecturer, Taylor's University

Nov 2015 - May 2016: Research Assistant, University of Malaya

Nov 2014 - Nov 2015: Research Fellow, University of Malaya

Sept 2012 - Sept 2014: Consultant, University of Malaya

July 2009 - July 2012: Postdoctoral Research Fellow, University of Malaya

Awards and Honours

2016

  • Hadiah Sanjungan awarded by Universiti Sains Malaysia

2001/2002

  • Dean’s List Semester 2 awarded by School of Chemical Sciences, Universiti Sains Malaysia.
  • Dean’s List Semester 1 awarded by School of Chemical Sciences, Universiti Sains Malaysia.

2000/2001

  • Dean’s List Semester 1 awarded by School of Chemical Sciences, Universiti Sains Malaysia.

1998/1999

  • Dean’s List Semester 2 awarded by School of Chemical Sciences, Universiti Sains Malaysia.

- Isolation, analysis and bioactivity of essential oils from medicinal plants

- Extraction, isolation and characterisation of bioactive secondary metabolites from medicinal plants

Scholarly Journals (Refereed Only)

2019

Kong Yong Loo, Kok Hoong Leong, Yasodha Sivasothy, Halijah Ibrahim and Khalijah Awang (2019). Molecular Insight and Mode of Inhibition of α-glucosidase and α-amylase by Pahangensin A from Alpinia pahangensis Ridl. Chemistry & Biodiversity, 16, e1900032. (Impact Factor: 1.449, ISI-Indexed)

Muhamad Aqmal Othman, Kohei Yuyama, Yuta Murai, Yasuyuki Igarashi, Daisuke Mikami, Yasodha Sivasothy, Khalijah Awang and Kenji Monde (2019). Malabaricone C as natural sphingomyelin synthase inhibitor against diet-induced obesity and its lipid metabolism in mice. ACS Medicinal Chemistry Letters,  10, 1154-1158. (Impact Factor: 3.737, ISI-Indexed)

2016

Siti Mariam Abdul Wahab, Yasodha Sivasothy, Liew Sook Yee, Marc Litaudon, Jamaludin bin Mohamad, Khalijah Awang (2016). Natural Cholinesterase Inhibitors from Myristica cinnamomea King. Bioorganic and Medicinal Chemistry Letters, 26, 3785-3792. (Impact Factor: 2.448, ISI-Indexed)

Muhamad Aqmal Othman, Yasodha Sivasothy, Chung Yeng Looi, Abdulwali Ablat, Jamaludin Mohamad, Marc Litaudon, Khalijah Awang (2016). Acylphenols and dimeric acylphenols from Myristica maxima Warb. Fitoterapia, 111, 12-17.  (Impact Factor: 2.431, ISI-Indexed)

Yasodha Sivasothy, Loo Kong Yong, Leong Kok Hoong, Marc Litaudon and Khalijah Awang (2016). A potent alpha-glucosidase inhibitor from Myristica cinnamomea King. Phytochemistry, 122, 265-269.  (Impact Factor: 2.905, ISI-Indexed)

2014

Yasodha Sivasothy, Chan Chee Ken Zachariah, Kok Hoong Leong and Khalijah Awang (2014). A novel heptacyclic diterpene from Alpinia pahangensis Ridley, a wild ginger endemic to Malaysia. Tetrahedron Letters, 55, 6163-6166.  (Impact Factor: 2.259, ISI-Indexed)

2013

Yasodha Sivasothy, Halijah Ibrahim, Audra Shaleena Paliany, Siti Aisyah Alias and Khalijah Awang (2013). A new bis-labdanic diterpene from the rhizomes of Alpinia pahangensis. Planta Medica, 79, 1775-1780.  (Impact Factor: 2.746, ISI-Indexed)

Yasodha Sivasothy, Halijah Ibrahim, Audra Shaleena Paliany, Siti Aisyah Alias and Khalijah Awang (2013). Pahangensin A and B, two new antibacterial diterpenes from the rhizomes of Alpinia pahangensis Ridley. Bioorganic and Medicinal Chemistry Letters, 23, 6280-6285.  (Impact Factor: 2.448, ISI-Indexed)

Yasodha Sivasothy, Shaida Fariza Sulaiman, Kheng Leong Ooi, Halijah Ibrahim and Khalijah Awang (2013). Antioxidant and antibacterial activities of flavonoids and curcuminoids from Zingiber spectabile Griff. Food Control, 30, 714- 720. (Impact Factor: 4.248, ISI-Indexed)

2012

Yasodha Sivasothy, A. Hamid A. Hadi,  Khalit Mohamad, Kok Hoong Leong, Halijah Ibrahim, Shaida Fariza Sulaiman, Kheng Leong Ooi, and Khalijah Awang (2012). Spectaflavoside A, a new potent iron chelating dimeric flavonol glycoside from the rhizomes of Zingiber spectabile Griff. Bioorganic and Medicinal Chemistry Letters, 22, 3831-3836. (Impact Factor: 2.448, ISI-Indexed)

2011

Yasodha Sivasothy, Wong Keng Chong, Abdul Hamid, Ibrahim M. Eldeen, Shaida Fariza Sulaiman and Khalijah Awang (2011). Essential oils of Zingiber officinale var. rubrum  Theilade and their antibacterial activities. Food Chemistry, 124, 514-517.  (Impact Factor: 5.399, ISI-Indexed)

2010

Wong Keng Chong, Yasodha Sivasothy, Boey Peng Lim, Hasnah Osman and Baharuddin Sulaiman (2010). Essential Oils of Etlingera elatior (Jack) R.M. Smith and Etlingera littoralis (Koenig) Giseke. Journal of Essential Oil Research, 22, 461-466. (Impact Factor: 1.270, ISI-Indexed)

Wong Keng Chong, Yasodha Sivasothy,  Boey Peng Lim and Baharuddin Sulaiman (2010). Essential Oils of Elettariopsis curtisii Bak. Journal of Essential Oil Research, 22, 533-535. (Impact Factor: 1.270, ISI-Indexed)

2006

Wong Keng Chong, Yasodha Sivasothy and  Boey Peng Lim (2006). Essential Oils of Elettariopsis smithiae Y.K. Kam and Elettariopsis rugosa (Y.K. Kam) C.K. Lim. Journal of Essential Oil Research, 18, 569-571. (Impact Factor: 1.270, ISI-Indexed)

Wong Keng Chong, Yasodha Sivasothy and  Boey Peng Lim (2006). Essential Oils of Elettariopsis slahmong C.K. Lim. Journal of Essential Oil Research, 18, 203-205. (Impact Factor: 1.270, ISI-Indexed)

Wong Keng Chong, Yasodha Sivasothy and Boey Peng Lim (2006) Essential oil of Elettariopsis elan  C.K. Lim. Flavour and Fragrance. Journal, 21, 562-564. (Impact Factor: 1.377, ISI-Indexed)

Books / Book Chapter

Yasodha Sivasothy, Keng Chong Wong and Peng Lim Boey. Phytochemical Studies of the Genera Elettariopsis and Etlingera: Chemotaxonomic Investigation, Isolation and Spectroscopic Studies. VDM Verlag 2011. Pg. 1-288.

Research Grants (Completed)

Type of Grant: Bantuan Kecil Penyelidikan (Project Number: BK002- 2015), University of Malaya
Title of Research: Antidiabetic labdane diterpenes from the rhizomes of Alpinia pahangensisRidley
Main Investigator: Dr. Yasodha Sivasothy
Co-Investigator: Dr. Leong Kok Hoong & Prof. Dr. Khalijah Awang
Date/Duration: 23rd January 2015 - 23rd June 2016
Amount: RM 38,000.00

Postgraduate (MSc)

Muhamad Aqmal Othman (MSc: Completed - 2016)
Acylphenols and dimeric acylphenols from Myristica maxima Warb
- Main Supervisor

Siti Mariam Abdul Wahab (MSc: Completed - 2016)
Natural cholinesterase inhibitors from Myristica cinnamomea King
- Main Supervisor

Audra Shaleena Paliany (MSc: Completed - 2014)  
Antibacterial activities of selected marine fungi from Peninsular Malaysia
- Co-supervisor

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