Brain Research Institute at Monash Sunway (BRIMS)

Monash Malaysia - BRIMSThe Brain Research Institute at Monash Sunway (BRIMS) is an internationally recognised Neuroscience platform affiliated with the Jeffrey Cheah School of Medicine and Health Sciences at Monash University Malaysia. BRIMS has contributed significantly to the growth of Brain Science since its establishment in 2006 as a small research lab.

Today, BRIMS takes pride on its cutting-edge facilities for researchers to conduct world-class research in Malaysia by providing our technical expertise as well as training opportunities.

Key focus areas

BRIMS focuses on the following five research areas:

Depression
This group aims to understand the cause of depression and anxiety from a range of aspects including biochemical, physiological, pharmacological, genetic, behavioural, environmental and social factors.

Drug Discovery
This group aims to establish human pluripotent stem cells (PSCs) and zebrafish as models for human brain diseases and for drug screening.

Addiction
This group aims to understand neuronal circuits linking negative emotion and addiction.

Neurodegeneration
This group utilises genomics approaches (transgenic and knock-out), single-cell gene expression analysis, DNA microarray, RNAi, and microRNA to address the molecular mechanism of age-related neurodegenerative diseases such as Alzheimer's and Parkinson's diseases.

Autism
Autism spectrum disorder (ASD) is associated with difficulties in social interaction, verbal and nonverbal communication and repetitive behaviours. This group aims to understand the neurochemical basis of autism.

Key expertise

  • Bioimaging
  • Functional Genomics
  • Neurochemistry
  • Stem cell (iPS cell)
  • SPF Rodent / Transgenic Fish

Specialist services

  • Histology/ Morphology
  • In-situ Hybridisation
  • Laser Capture Micro Dissection
  • Deep Tissue 3D Imaging of Fixed Sample
  • Immunohistochemistry/ Cytochemistry
  • Fluorescent In Situ Hybridisation
  • Fluorescent Immunohistochemistry/ Cytochemistry
  • High Speed Live Confocal Imaging
  • Ca2+ Imaging
  • Photostimulation Analysis
  • Extraction, Isolation and Characterisation (plant / compound)
  • Toxicity Test (In Vitro)
  • Pharmacological Screening (In Vitro)
  • Molecular Pharmacological Study (In Vitro/ In Vivo)
  • Reporter Assay (In Vitro)
  • Behaviour Analysis

Explore more on neuroscience here at BRIMS.