PhD/Master studenship (Prof Sunil K. Lal) 3
Project Title: Genomics and proteomics studies on mammalian cells following viral infection.
Description of the project:
Sporadic outbreaks of epizootics like Ebola, SARS, Avian and Swine Flu remind us of the potential for communicable diseases to quickly spread into worldwide epidemics. Despite improved surveillance and quarantine measures, we find ourselves in the midst of a H1N1 and H7N9 influenza pandemic. Effective and new therapeutic targets are essential to protect against current and future pandemics and the best route to achieving this is through a detailed and global view of virus–host interactions. To prepare for future influenza outbreaks, it is necessary to understand how the virus interacts and manipulates the host pathways and to determine what makes certain strains of influenza highly pathogenic. Traditionally we have been a dynamic molecular biology laboratory with a focus on studying virus-host relationships and discovering how viruses exploit the cellular machinery to their advantage. We have deployed a variety of experimental systems that allow current models to be refined and thus provide us the basis for further predictions and hypothesis generation. By examining these changes in a comprehensive manner, we have been able to discover exciting new insights into innate immunity, cytokine and cell signalling, cell survival and proliferation thus shedding new vision on strategies used by influenza viruses to overcome these cellular barriers. Research from students has resulted in high impact publications leading to dynamic placements for a strong career. Using modern genomics platforms we intend to study genomic, transcriptomic and proteomic changes in calls infected with Influenza A virus. State-of-the-art genomics platforms exist on Monash campus to perform research in this area which will result in excellent research data on this important subject and will help in understanding the molecular biology of virus infected cells.
The position is available to Malaysian and International students. Candidates should have a Bachelor degree in Science related discipline with 1st or 2nd upper class honours or equivalent.
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For Master requirements, please refer to this link: Master
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Level of support
Scholarship will be awarded on a competitive basis.
For further details, please refer to this link.
Application is on a first come first serve basis. Once a suitable candidate is found, the application will be closed.
Only eligible candidates should submit an application and resume directly to Prof. Sunil K. Lal (email@example.com)