Cheow Yuen Lin



PhD (Nanyang Technological University, Singapore)
Telephone: (+603) 5514 6000,
Ext: 44401 (DID: 5514 4401)
Room number: 4-8-38 (Building 4, Level 8, No. 38)

Natural Product Chemistry, Organometallic Chemistry

1. Synthesis of metal carbene complexes and evaluation of its biological properties.

2. Chemical isolation, structure elucidation and biological properties of natural products from Malaysian tropical plants

The research activities in my group revolve around drug discovery, design and development. My research is largely focused on natural product chemistry and bioorganometallic chemistry specifically discovering compounds as potential anticancer and antimicrobial agents. Our lab is isolating and characterising bioactive compounds from Malaysian tropical plants and bacteria obtained from tropical peat swamp forest soil. The ecosystem biodiversity in Malaysia is among the world richest and its potential as a vast pharmaceutical store bank has been cited by many scientists.  As a natural product chemist, I collaborate with my colleagues and discover a myriad of interesting chemistry and biology from our ecosystem. I also undertake scholarly activity to make organometallic complexes and evaluate their biological properties.

Si Hui Chen, Si Ling Ng, Yuen Lin Cheow, Adeline Su Yien Ting. A novel study based on adaptive metal tolerance behavior in fungi and SEM-EDX analysis. Journal of Hazardous Materials. 2017. Volume 334, Pages 132–141 DOI:

Biswas, Nirupam ; Cheow, Yuen Lin ; Tan, Chin Ping ; Siow, Lee Fong Physical, rheological and sensorial properties, and bloom formation of dark chocolate made with cocoa butter substitute (CBS). Submitted to LWT-Food Science and Technology. 2017. Article in press

Biswas, Nirupam ; Cheow, Yuen Lin ; Tan, Chin Ping ; Kanagaratnam, Sivaruby; Siow, Lee Fong, Cocoa Butter Substitute (CBS) Produced from Palm Mid-fraction/Palm Kernel Oil/Palm Stearin for Confectionery Fillings , Journal of the American Oil Chemists Society. 2017, Volume: 94, pp 235-245.

Cheong, Siew Loon; Cheow, Yuen Lin; Ting, Adeline Su Yien , Characterizing antagonistic activities and host compatibility (via simple endophyte-calli test) of endophytes as biocontrol agents of Ganoderma boninense , Biological Control. 2017 Volume: 105, pp 86-92.

Ong, Kuan Shion ;  Aw, Yoong Kit ; Lee, Learn Han ; Yule, Catherine M; Cheow, Yuen Lin; Lee, Sui Mae,  Burkholderia paludis sp nov., an Antibiotic-Siderophore Producing Novel Burkholderia cepacia Complex Species, Isolated from Malaysian Tropical Peat Swamp Soil , Frontiers in Microbiology. 2016, Volume: 7 DOI: 10.3389/fmicb.2016.02046

Biswas, Nirupam ; Cheow, Yuen Lin ; Tan, Chin Ping ; Siow, Lee Fong, Blending of Palm Mid-Fraction, Refined Bleached Deodorized Palm Kernel Oil or Palm Stearin for Cocoa Butter Alternative.  Journal of the American Oil Chemists Society. 2016, Volume: 93, pp 1415-1427.

Yoong Kit Aw, Kuan Shion Ong, Catherine Mary Yule, Yuen Lin Cheow, Learn-Han Lee, Sui Mae Lee (2016). Newly isolated Paenibacillus tyrfis sp. nov., from Malaysian tropical peat swamp soil with broad spectrum antimicrobial activity. Frontiers in Microbiology, 7(219), 1-9. doi:

Yuen Lin Cheow, Sumod A. Pullarkat, Yongxin Li, Pak-Hing Leung (2012). Asymmetric hydroarsination reactions toward synthesis of alcohol functionalised C-chiral As-P ligands promoted by chiral cyclometallated complexes. Journal of Organometallic Chemistry, 696, 4215-4220.

Sumod A. Pullarkat, Yuen Lin Cheow, Yongxin Li and Pak-Hing Leung (2009).  Enantioselective, High-yielding Synthesis of Alcohol-Functionalised Diphosphanes Utilizing Asymettric Control with a Chiral Auxilliary. Eur. J. Inorg. Chem., 2375-2382.

Gwendoline Cheng Lian Ee, Yuen Lin Cheow (2008). Secondary Metabolites from two Garcinia Species and their Biological Acitivities, Asian J. of Chem. Vol 20, 343-351.

G.C.L.Ee, A.S.M.Kua, Y.L Cheow, C.K.Lim, V. Jong and M. Rahmani (2004). A new pyranoxanthone Inophyllin B from Calophyllum inophyllum (Guttiferae). Natural Product Sciences, 2004, 10(2), 220-222.

PhD Students (Present)

  1. Steven Aw Yoong Kit (co-supervision) 
  2. Nirupam Biswas (co-supervision)
  3. Ong Kuan Shiong  (co-supervision) 
  4. Cheong Siew Loon (co-supervision)
  5. Yaw Chong Wey (co-supervision) 
  6. Wong Kak Ming (co-supervision) 
  7. Choo Kar Bee (main supervision)
  8. Carrie Sim Siew Fang (co-supervision)
  9. Chen Si Hui (co-supervision)
  10. Krystle Angelique Aguda Santiago (co-supervision)
  11. Mah Wee Li (main supervision)

Honours Students (Completed)

  1. Gabrial Ong Ching Shien (co-supervision)
  2. Mah Wee Li (main supervision)

Best Poster Award

  • Best poster presentation. Mah Wee Li, Lee Sui Mae, Choo Kar Bee, Cheow Yuen Lin. 2016. Synthesis and Evaluation of anti-microbial activities of Pd-N Heterocyclic Carbene Complexes. Monash Science Symposium 2016 21-23 November 2016.

Journal reviewer

  • Natural Product Research