Lim Yau Yan
School of Science
Associate Professor Lim Yau Yan began his academic career as a lecturer in chemistry in 1971 at the University of Malaya after obtaining a PhD in Physical Inorganic Chemistry from the University Of Illinois, Urbana, USA. He retired from University of Malaya in 1998 as a Professor and began his current role at Monash University Malaysia in the same year. Currently he is an Associate Professor teaching Inorganic, Chemistry, Medicinal chemistry and Analytical Chemistry/Spectroscopy at all year levels.
Associate Professor Lim's research interests are diverse, from micellar catalysis based on surface active transition metal complexes to the identification and bioactivity of active compounds from herbal plants
, ,and to studying the effects of processing treatment on the bioactivity of herbal plants. He leads a successful research team consisting of several PhD and Honours students. Since starting work at Monash, ten PhD and one MSc students have successfully graduated with four of them now in academia with independent research careers.
He has been a member of the Review Panel of Malaysian Qualification Agency (MQA) for more than ten years. He has also served as a member of Technical Committee (Chemicals) of Standard Institute Malaysia in 1990’s. Associate Professor Lim is an elected Fellow of the Malaysian Academy of Sciences based on his significant contributions to chemical research and chemistry education.
- Doctor of Philosophy in Physical Inorganic Chemistry, University of Illinois, USA, 1971
- Bachelor of Science (Honours), University of Malaya, 1966
- Food chemistry, natural products, inorganic chemistry
- Antioxidants, Bioactivity, herbal plants processing - drying, transition metal chemistry
- CHM2911 (Inorganic and Organic Chemistry)
- CHM2922 (Spectroscopy and Analytical Chemistry)
Yew PN, Goh BH, Lim YY, Lee WL* (2018) Gastrointestinal bezoar stones: Current knowledge and future perspective on the potential of plant-derived phytobezoar in cancer treatment. In Anticancer Plants: Natural Products and Biotechnological Implements (Vol. 2). Springer, 19-39.
Hikari Kan Fu Oh, Lee Fung Siow, Yau Yan Lim. 2019. Approach to preserve phenolics in Thunbergia laurifolia leaves by different drying treatments. Journal of Food Biochemistry, e12856.
Hui-Li Tan, Dan Kai, Pooria Pasbakhsh, Sin-Yeang Teow, Yau-Yan Lim, Janarthanan Pushpamalar. 2019. Electrospun cellulose acetate butyrate/polyethylene glycol (CAB/PEG) composite nanofibers: A potential scaffold for tissue engineering. Colloids and Surfaces B: Biointerfaces, -, 110713.
D Daniel-Jambun, KS Ong, YY Lim, JBL Tan, SW Yap, SM Lee. 2019. Bactericidal and cytotoxic activity of a diarylheptanoid (etlingerin) isolated from a ginger (Etlingera pubescens) endemic to Borneo. Journal of Applied Microbiology, 127 (1), 59-67.
Peng-Nian Yew, Yau-Yan Lim, Wai-Leng Lee. 2019. Tannic acid-rich porcupine bezoars induce apoptosis and cell cycle arrest in human colon cancer cells. Pharmacognosy Magazine, 15(65), 523.
Catherine M Yule, Yau Yan Lim, Tse Yuen Lim. 2018. Recycling of phenolic compounds in Borneo’s tropical peat swamp forests. Carbon Balance and Management, 13(1), 3.
Kuan Shion Ong, Christina Injan Mawang, Delhousie Daniel-Jambun, Yau Yan Lim, Sui Mae Lee. 2018. Current anti-biofilm strategies and potential of antioxidants in biofilm control. Expert Review of Anti-infective Therapy, 16(11), 855-864.
Zhi Hung Loh, Yau Yan Lim. 2018. Drying effects on antioxidant activity, enzyme activity, and phytochemicals of avocado (Persea americana) leaves. Journal of Food Processing and Preservation, 42(10), e13667.
Delhousie Daniel-Jambun, Kuan Shion Ong, Yau Yan Lim, Joash Ban Lee Tan, Wai Leng Lee, Azira Muhamad, Sau Wai Yap, Sui Mae Lee. 2018. Antioxidant properties of Etlingera pubescens, an edible ginger plant endemic to Borneo. Food Bioscience, 25, 44-51.
J Pushpamalar, SJ Langford, MB Ahmad, YY Lim, K Hashim. 2018. Eco-friendly smart hydrogels for soil conditioning and sustain release fertilizer. International Journal of Environmental Science and Technology, 15(10), 2059-2074.
Yik-Ling Chew, Yau-Yan Lim. 2018.Evaluation and Comparison of Antioxidant Activity of Leaves, Pericarps and Pulps of Three Garcinia Species in Malaysia. Free Radicals & Antioxidants, 8(2), 130-134
Zhi Hung Loh, Hikari Kan Fu Oh, Yau Yan Lim. 2018. Relationship between polyphenol oxidase activity and phenolics degradation on ambient air‐drying of herbal plants. Journal of Food Processing and Preservation, 42(7), e13672.
Li Yoke Ho, Yau Yan Lim, Chin Ping Tan, Lee-Fong Siow. 2018. Comparison of physiochemical properties and aqueous solubility of xanthone prepared via oil-in-water emulsion and complex coacervation techniques, International Journal of Food Properties, 21, 1, 784-798
Lai HY, Lim YY, and Kim KH. Isolation and characterisation of aproanthocyanidin with antioxidative, antibacterial and anti-cancer properties from fern Blechnum orientale. Pharmacogonosy Magazine, 2017:13:31-37. DOI: 10.4103/0973-1296.197659
Saik A Y H, Lim YY, Stanslas, and Choo WS .Enzymatic synthesis of quercetin oleate esters using Candida antarctica lipase B. Biotechnology Letters, 2017, 39(2), 297-304. DOI 10.1007/s10529-016-2246-5
Loh JY, Lim YY and Ting ASY. Bacteriocin-like substances produced by Lactococcus lactis subsp. lactis CF4MRS isolated from fish intestine: Antimicrobial activities and inhibitory properties. International Food Research Journal, 2017, 24(1), 394-400.
Yew PN, Lee WL,and Lim YY. Antioxidant and Intracellular ROS/RNS Scavenging Activities of three Porcupine Bezoars from Hystrix brachyuran. Pharmacogonosy Research, 2017, 9:366-71. DOI:10.4103/pr.pr_145_16
Daniel D, Dwiyanto J, Lim YY, Tan JBL,Muhamad A, Yap SW, Lee SM. Investigation on the antimicrobial activities of gingers (Etlingera coccinea (Blume) S.Sakai & Nagam and Etlingera sessilanthera R.M.Sm.) endemic to Borneo. Journal of Applied Microbiology, 2017, 123 (4), 810-818. DOI: 10.1111/jam.13536
Mawang C, Lim YY, Ong K S, Muhamad A, Lee SM. Identification of α-tocopherol as a bioactive component of Dicranopteris linearis with disrupting property against pre-formed biofilm of Staphylococcus aureus. Journal of Applied Microbiology, 2017, 123(5), 1148-1159. DOI:10.1111/jam.13578
Lim TY, Lim YY and Yule CM. Distribution and Characterisation of Phenolic Compounds in Macaranga Pruinosa and Associated Soils in a Tropical Peat Swamp Forest. Journal of Tropical Forest Science, 2017, 29(4), 509-518.
Karthik D, Saravanan M, Lim Y Y, & Pushpamalar J. Electron beam radiation mediated green synthesis of silver nanoparticles using carboxymethyl sago pulp obtained from sago waste. Polymer, 2016, 86, 147-156.
Yule C M, Lim YY, and Lim TY. Degradation of Malaysian peatlands decrease levels of phenolics in soil and in leaves of Macaranga pruinosa. Frontiers in Earth Science, 2016, 4:45.
Anand K V, Thenapakiam S, Saravanan M*, Pushpamalar J, S J Langford, Lim Y Y. Optimizing Extraction of Cellulose and Synthesizing Pharmaceutical Grade Carboxymethyl Sago Cellulose from Malaysian Sago Pulp. Applied Sciences, 2016, 6, 170
Tan J B L, Lim Y Y and Lee S M. Antioxidant and antibacterial activity of Rhoeo Spathacea (Swartz) Stern leaves. J Food Sci and Technology, 2015, 52, 2394-2400.
Tan J J Y, Lim Y Y, Siow L F, Tan J B L. The effect of polyphenol oxidase on the antioxidant activity of dried Morus alba leaves. J Food Preservation and Processing, 2015, 39, 2811-2819.
Tan J B L, Lim Y Y and Lee S M. Antioxidant and antibacterial activity of Rhoeo Spathacea (Swartz) Stern leaves. J Food Sci and Technology, 2015, 52, 2394–2400
Wong S K, Lim Y Y, Ling S K and Chan E W C. Caffeoylquinic acids in leaves of selected Apocynaceae species: their isolation and content. Pharmacognosy Research, 2014, 6, 67-72.
Lim T Y, Lim Y Y and Yule C M. Bioactivity of Macaranga leaves in tropical peat swamp and non-peat swamp environments. Journal of Tropical Forest Science, 2014, 26, 134-141.
Wong S K, Lim Y Y, Ling S K and Chan E W C. Antiproliferative activity of Valaris glabra Kuntz (Apocynaceae). Pharmacognosy Magazine, 2014, 10, S232-S239.
Tan J B L, Lim Y Y and Lee S M. Rhoeo spathacea (swartz) stearn leaves, a potential natural food colorant. J Functional Foods, 2014, 7, 443-451.
Loh J Y, Lim Y Y, Harmin S A, and Ting A S Y. In vitro assessment on intestinal microflora from commonly farmed fishes for control of the fish pathogen Edwardsiella tarda. Turk J Vet Anim Sci., 2014, 38, 257-263.
Chew Y L, Lim Y Y, Stanslas J, Ee G C L, Goh J K. Bioactivity-guided isolation of anticancer agents from bauhinia kockiana korth. Afr J Tradit Complement Altern Med., 2014, 11, 291-299.
Tan J B L, Yap W J, Tan S Y, Lim Y Y, Lee S M. Antioxidant content, antioxidant activity and antibacterial activity of five plants from the Commelinaceae family. Antioxidants, 2014, 3, 758-769
Pushpamalar V, Langford S, Ahmad M and Lim Y Y. Preparation of Carboxymethyl Sago Pulp Hydrogel from Sago Waste by Electron Beam Irradiation and Swelling Behaviour in Water and Various pH Media. Journal of Applied Polymer Science, 2013, 128, 451-459.
Pushpamalar V, Langford S, Ahmad M, Hashim K B and Lim Y Y. Adsorption Characterization of Ca2+, Na+ and K+ on Irradiation Crosslinked Carboxymethyl Sago Pulp Hydrogel. Journal of Applied Polymer Science, 2013, 128, 1828-1833.
Wong SK, Lim YY, Chan EWC, (2013) Botany, uses, phytochemistry and pharmacology of Apocynaceae species: A review. Pharmacognosy Communications, 3(3), 2–11.
Chong K L, and Lim Y Y. Effects of Drying on the Antioxidant Properties of Herbal Tea from Selected Vitex species. Journal of Food Quality, 2012, 35, 51-59.
Chong, K.L. And Lim, Y.Y. (2012), Effects Of Drying On The Antioxidant Properties Of Herbal Tea From Selected Vitex Species. Journal Of Food Quality, 35: 51–59. Doi: 10.1111/J.1745-4557.2011.00422.X
Wong S K, Lim Y Y, Abdullah N R, Nordin F J (2011) Antioxidant, antiproliferative and antiplasmodial activities of leaf extracts of five Apocynaceae species. BMC Complementary and Alternative Medicine 11:3
Chew YL, Chan EWL, Tan PL, Goh JK, Lim Y Y (2011) Preliminary assessment on phytochemical content, polyphenolic composition, antioxidant and antiobacterial activities of Leguminosae medicinal plants in Peninsular Malaysia. BMC Complementary and Alternative Medicine 11:12
Wong S K, Lim Y Y, Abdullah N R and Nordin F J. Antioxidant, antiproliferative and antiplasmodial activities of leaf extracts of five Apocynaceae species. BMC Complementary and Alternative Medicine, 2011, 11:3
Chan E W C, Lim Y Y, and Tan S P. Standardised herbal extract of chlorogenic acid from leaves of Etlingera elatior (Zingiberaceae). Pharmacognosy Research, 2011, 3, 178-184.
Chew Y L, Chan E W L, Tan P L, Goh J K, and Lim Y Y. Preliminary assessment on phytochemical content, polyphenolic composition, antioxidant and antiobacterial activities of Leguminosae medicinal plants in Peninsular Malaysia. BMC Complementary and Alternative Medicine, 2011, 11:12
Wong S K, Lim Y Y, Abdullah N R and Nordin F J. Antiproliferative and phytochemical analyses of leaf extracts of ten Apocynaceae species. Pharmacognosy Research, 2011, 3, 100-106.
Chan E W C, Lim Y Y, and Wong S K. Antioxidant properties of ginger leaves: An overview. Free Radicals and Antioxidants, 2011, 1, 6-16.
Lai H Y and Lim Y Y. Evaluation of Antioxidant Activities of the Methanolic Extracts of Selected Ferns in Malaysia. International Journal of Environmental Science and Development, 2011, 2, 442-447.
Chan EWC, Lim Y Y, Chong KL, Tan JBL, Wong SK (2010) Antioxidant properties of tropical and temperate herbal teas. Journal of Food Composition and Analysis 23: 185-189
Lai HY, Lim Y Y (2010) Blechnum orientale Linn- A fern with potential as antioxidant, anticancer and antibacterial agent. BMC Complementary and Alternative Medicine 10:15
Chan E W C, Lim Y Y, Chong K L, Tan J B L, Wong S K. Antioxidant properties of tropical and temperate herbal teas. Journal of Food Composition and Analysis, 2010, 23, 185-189.
Lai H Y and Lim Y Y. Blechnum orientale Linn- A fern with potential as antioxidant, anticancer and antibacterial agent. BMC Complementary and Alternative Medicine, 2010, 10:15
Chan E W C, Lim Y Y and Nor Azah M A. Composition and antibacterial activity of essential oils from leaves of Etlingera species (Zingiberaceae). International Journal for the Advancement of Science and Arts, 2010, 1, 1-12.
Lim Y.Y., 2014, Bioactivity investigations on the extracts of porcupine date, Soon Hing Cheong (Ginseng) Sdn Bhd
Lim, Y.Y., 2014, Determining the factors affecting changes in antioxidant properties of herbal leaves subjected to thermal drying, Ministry of Higher Education, RM118k
PhD Students (Present)
- Hikari Oh Kan Fu
- Yew Peng Nian
- Janet Tan
PhD Students (Completed)
- Eric Chan Wei Chiang: Bioactivities and Chemical Constituents of Leaves of Some Etlingera Species (Zingiberaceae) in Peninsular Malaysia (2009)
- Lai How Yee: Bioactivities and Chemical Constituents of Several Ferns in Malaysia, with Emphasis on Blechnum Orientale Linn. (2010)
- Chew Yik Ling: Bioactivity and Chemical Constituents of Selected Medicinal Plants from Leguminosae Family in Malaysia (2011)
- Lim Tse Yuen: Environmental Effects Affecting Phenolic Production in Macaranga pruinosa in the Tropical Peat Swamp Forest (2012)
- Wong Siu Kuin: Bioactivities and Chemical Constituents of Leaves of Selected Apocynaceae Species in Peninsular Malaysia (2013)
- Joash Tan Ban Lee: Bioactivity and Chemical Constituents of Rhoeo Spathacea and Rhoeo Discolor with emphasis on R Spathacea (2013)
- Chung Felicia Fei Lei: Potential Effects of Cerbera Odollan Leaf Extracts and Neriifolin Exposure in Breast Cancer Treatment and Progression (2014)
Honours Students (Completed)
- Ivan Pradipta (2014)
- Janet Tan Jia Yin(2014)
- Yong Ee Wing Joshua (2010)
- Joash Tan Ban Lee (2010)
- Chong Kok Leong (2009)
- Lee Shu Mei (2009)
- Wong Siu Kuin (2008)
- Tan Shiau Pin (2008)
- Lim Kim Kiat(2007)
- Chew Yik Ling(2007)
- Christina Evy Koe (2006)
- Kavinash Loganathan (2006)
- Wong Li Fang (2006)
- Lim Yat Yan (2006)
- Johannes Murtijaya (2005)
- Eric Chan Wei Chiang (2005)
- Elaine Quah Phaik Ling (2005)
- Eileen Ngieng (2004)
- Ginny Lim Theng Teng (2003)
- Liew Li Phing (2002)
- Loh Zhi Hung (2017)
3rd Year Project (Completed)
- Fung Jia Jun (2017)
- Kueh Ying Hui (2017)
- Tan Hsin Yen
- Nur Zawanah Zabidi
- Hafiz Bin Zaaimuddin
Membership in Academic Editorial Committees
- Heliyon (Editorial Board)
- Food Chemistry (Journal reviewer)
- Journal of Food Science (Journal reviewer)
- Journal of Food Science and Technology (Journal reviewer)
- LWT - Food Science and Technology (Journal reviewer)
- Pharmaceutical Biology (Journal reviewer)
- Molecules (Journal reviewer)
- Journal of Ethnopharmacology (Journal reviewer)
- BMC Complementary & Alternative Medicine (Journal reviewer)
- Malaysian Journal of Chemistry (Journal reviewer)
Engagement with premier Public Universities
- University Malaya Graduate School (External Examiner for higher degree candidates)
Member of Professional Bodies
- Academy of Sciences Malaysia (Fellow)
- Malaysian Institute of Chemistry (Member)