CMR Projects
Cardio-metabolic
Principal Researcher | Co-Researchers | Project Title: |
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Professor Dato’ Anuar Zaini | Dr Badariah. Ahmad, Dr Nik Asmah Nik Hussain, Dr Quek Kia Fatt | 1. Cardio-metabolic risk − Intra-abdominal Adiposity, 5A Registry 2. Switch from existing to another Insulin treatment in inadequately controlled diabetes |
Dr Khalid Abdul Kadir | Dr Paul Fullerton, Dr Cheryl Fullerton | General practitioners implementation of normoglycaemic target (GIANT) |
Dr Khalid Abdul Kadir | 1. Sitagliptin and Pioglitazine in Type 2 Diabetes 2. MK-0364 in Overweight and Obese with Type 2 diabetes | |
Dr Paul Ling Kah Hing | Professor Dato’ Khalid Abdul Kadir | 1. Clinical efficacy of a novel cholesterol agent in elevating HDL 2. Efficacy and safety of MK-0524B Combination tablet Compared to MK0524A + Simvastation Co- administration in Primary Hypercholesterolemia |
Dr Paul Ling Kah Hing | Extended Release (ER) Niacin/Laropiprant in Type 2 Diabetes |
Clinical trial
Principal Researcher | Co-Researchers | Project Title: |
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Dr Paul Ling Kah Hing | Dr Khalid Abdul Kadir | 1. A Phase 3 Randomized, Double-blind, Parallel-group, Multi-center Study of the Safety and Efficacy of Apixaban for Prophylaxis of Venus Thromboembolism in Acutely Ill Medical Subjects During and Following Hospitalization. NMRR-08-1034-2189 2. A Randomized, Double-Blind, Active-Controlled, Multicenter Study of Patients with Primary Hypercholesterolemia and High Cardiovascular Risk and not Adequately Controlled with Atorvastatin 20 mg: A Comparison of Switching to a Combination Tablet Ezetimibe/Simvastatin (10mg/40mg) versus Doubling the Baseline Dose to Atorvastatin 40 mg. NMRR-08-1355-2744 3. A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Lipid -Modifying Effect and Tolerability of MK1903 in Patients with Dyslipidemia. ID: 3062 4. A 76 Week, Worldwide, Multicenter, Double-Blind, Randomized Placebo Controlled Study to Assess the Tolerability and Efficacy of MK-0859 When Added to Ongoing Therapy with A Statin in Patients with Hypercholesterolemia or Mixed Hyperlipidaemia. NMRR-08-362-1517 5. MK0736 Protocol 007 - A worldwide, multicenter, double blind, randomized, placebo controlled, dose ranging study to evaluate the efficacy, safety and tolerability of Mk-0736 when added to ongoing therapy with ACE inhibitor or ARB in patients with diabetes and hypertension. NMRR -08-1354-275 |
Cost effectiveness of cardiology intervention
Principal Researcher | Co-Researchers | Project Title: |
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Dr Sivalal Sadasivan | Dr Christine Kennedy, Dr S. Selvamalar, Dr Amudha Kadirvelu. | Cost-effectiveness of PCI (percutaneous coronary intervention) and CABG |
Diabetes Complications and risk factors
Principal Researcher | Co-Researchers | Project Title: |
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Dr Amudha Kadirvelu | Dr Suriati bt Hashim, Dr Rokiah Pendek, Dr Sivalal Sadasivan, Dr Shajahan Yasin, Dr Anuar Zaini Md Zain | Prevalence of Diabetic complications and its risk factors |
Dr Christina Gertrude Yap | Dr Anuar Zaini Md Zain, Dr Iekhsan Othman | Early predictors of Risk of Diabetic Nephropathy |
Diabetes and obesity
Principal Researcher | Co-Researchers | Project Title: |
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Dr Anuar Zaini Md Zain | Dr Khalid Abdul Kadir, Dr Nik Asmah Nik Hussain, Dr Badariah Ahmad, Dr Siti Harnida Md Isa, Dr Iekhsan Othman, Dr Quek Kia Fatt, Dr Shamsul Haque, Dr Lenore Manderson, Dr Brian Oldenburg | Metabolic Response in Treatment of Diabetes with Concomitant Obesity |
Dr Khalid Abdul Kadir | 1. Diabetes in Obese Patients 2. 11-b Hydroxysteroid Dehydrogenase in Diabetes & Metabolic Syndrome | |
Dr Paul Ling Kah Hing | Efficacy of Lipid Lowering in Type 2 Diabetes | |
Dr Siti Harnida Md Isa | Dr Khalid Abdul Kadir, Dr Paul Ling Kah Ling, Dr Paul Fullerton, Dr Leong Chui Chui | Metabolic Syndrome Study in Malaysia |
Dr Siti Harnida Md Isa | Dr Khalid Abdul Kadir Nazaimoon Wan Mohamed (IMR), Dr Anuar Zaini Md Zain, Dr Maude Phipps, Dr Badariah Ahmad and Dr Jamilah Ariffin | Diabetes and Metabolic Syndrome Study in Orang Asli – an extension of the Malaysian Metabolic Syndrome Study |
Disease management
Principal Researcher | Co-Researchers | Project Title: |
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Dr Anuar Zaini Md Zain | Dr Badariah Ahmad, Dr Amudha Kadirvelu., Dr Sivalal Sadasivan | Effectiveness of Current Interventions for Diabetes Mellitus |
Epidemiology and human genetics
Principal Researcher | Co-Researchers | Project Title: |
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Dr Maude Elvira Phipps | Timothy Adrian Jinam (National Institute of Genetics, Japan), S. Saitou (National Institute of Genetics, Japan), Edison Liu(Genome Institute of Singapore), Jin Li (Fudan University, China), Mahmood Ameen (UM), Juli Edo (UM), Pan Asia SNP Consortium | Mapping the genomic architecture of Asian populations as a reference point for translational medicine and disease studies. |
Health education and delivery
Principal Researcher | Co-Researchers | Project Title: |
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Dr Nik Asmah Nik Hussain | Dr Quek Kia Fatt, Dr Anuar Zaini, Dr Badariah Ahmad, Dr Siti Harnida, Dr Brian Oldenburg, Dr Lenore Manderson | Effectiveness of Health Education on Ischemic Heart Disease (IHD) Outcomes |
Dr Sivalal Sadasivan | Health Care delivery to improve outcomes for IHD |
Intensive care
Principal Researcher | Co-Researchers | Project Title: |
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Dr Nor'Azim Mohd Yunos | Dr Rafidah Atan | Effects of intensive insulin therapy protocols on critically ill patients in intensive care |
Patient participation in diabetes
Principal Researcher | Co-Researchers | Project Title: |
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Dr Badariah Ahmad | Dr Siti Harnida Md Isa, Dr Shamsul Haque, Dr Nik Asmah Nik Hussain, Dr Quek Kia Fatt, Dr Anuar Zaini Md Zain, Dr Brian Oldenburg, Dr Lenore Manderson, Dr Khalid Abdul Kadir | Malaysian Diabetes & Research on Lifetime Lifestyle Intervention (MY-DARLING) |
Screening in diabetes
Principal Researcher | Co-Researchers | Project Title: |
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Dr Amudha Kadirvelu | Dr Sivalal Sadasivan, Dr Nik Asmah Nik Hussain, Dr Khalid Abdul Kadir | Micro-Albuminuria and Endothelial Dysfunction in Pre-diabetic |