Actinomycetota: Are They Still Relevant in Drug Discovery

Abstract:

Actinomycetota or synonymy known as Actinobacteria is a phylum of mostly Gram-positive bacteria that has been explored extensively as a source of antibiotics and secondary metabolites. Actinomycete drug resources have been utilized and developed for many years, causing the identification of new active structural substances to become difficult due to the re-isolation of the same molecules. Hence, repurposing the existing compounds is one way to discover new therapeutics outside the scope of the original use.

Speaker's Profile:

Dr. Adzzie Shazleen binti Azman has been a lecturer in microbiology at the School of Science since August 2020 after her postdoctoral training at Universiti Malaya. In her PhD, she studied taxonomy and diversity via polyphasic approaches and the secondary metabolite of Actinobacteria at Jeffrey Cheah School of Medicine and Health Science, MUM, where she found one novel genus and two novel species of rare Actinobacteria. Her current focus is investigating and discovering the antimicrobial, antibiofilm, and mechanisms of selected pure compounds from Actinobacteria.