Developing early breast cancer detection
In the world of complex cancer research, Aathira Sujathan Nair, a PHD student from the School of Pharmacy, stands by her dedication to making early detection of breast cancer more accessible and accurate. Recently, Aathira won the 2024 Monash Graduate Association (MGA) People’s Choice Award at the Monash University Three Minute Thesis (3MT) competition. Her presentation, titled “Glowing Tags: Spotting Breast Cancer Cells,” explored the use of fluorescence probes as a powerful diagnostic tool to detect cancer at an early stage.
Aathira’s journey into the world of pharmacy and research began in India, where she gained her Bachelor’s and Master’s degrees from Amrita School of Pharmacy. Reflecting on her early career, her passion for research came from her father, inspiring her to contribute to the healthcare system. However, she decided to pursue research during her final year of undergraduate studies. “After completing my studies, I worked full-time in a pharmacy while also spending a year teaching. During this time, I realised that the typical 8-5 pm job lacked the intellectual excitement I sought, leading me to pursue a career in research,” she stated.
Aathira presents her research on early breast cancer detection at the 2024 Monash Graduate Association (3MT) competition.
Aathira’s research focuses on one of healthcare’s biggest challenges which is detecting cancer before it develops. Her work emphasises on identifying breast cancer cells at a much earlier stage by using fluorescent probes. She believes this early detection could transform patient outcomes. “Cancer is often detected at an advanced stage, when treatment options may be limited. Fluorescent probes offer the potential to spot cancer cells at an early stage.”
According to Aathira, the idea of using 'glowing tags' to detect breast cancer cells came during her preparation for the 3MT presentation. She sought feedback from Associate Professor Anton V. Dolzhenko, her American Chemical Society (ACS) Advisor, who guided her to shape the research narrative effectively. By using fluorescence probes, her goal is to identify cancer cells earlier, potentially leading to more effective treatments in the near future.
When asked about her inspiration on exploring this area of study, Aathira credits her supervisor Dr Thet Thet Htar from the School of Pharmacy, “As a chemist, I was particularly motivated by my supervisor’s innovative approach on moving beyond conventional treatment research to explore something different and impactful.” This change in view pushed her to the potential of exploring new path in cancer research, which eventually led her to focus on breast cancer. In addition to her supervisor’s guidance, Aathira acknowledges the support she received through the Fundamental Research Grant Scheme (FRGS) from the Ministry of Higher Education (MOHE).
Aathira received the Monash Graduate Association (MGA) People’s Choice Award 2024 certificate from Professor Nellie Georgiou-Karistianis, Pro-Vice Chancellor (Research Training).
Aathira envisions her research to contribute to significant advancements in breast cancer diagnostics. “This advancement could significantly transform current approaches to early detection, ultimately improving patient outcomes and survival rates.” With a pharmacy background, she focuses on identifying challenges in expanding diagnostic probes for breast cancer while better understanding patients' viewpoints. This approach helps her navigate research complexities and ensures her work benefits those affected by breast cancer.
Aathira’s advice to fellow PhD students and young researchers interested in pursuing postgraduate studies at the School of Pharmacy: “It is a field rich with opportunities in innovative research and healthcare solutions.” She shares that the support she received at Monash University Malaysia has been invaluable. Despite their busy schedules, her supervisors made time to review her work and provide guidance which she found instrumental to her growth.
If you are looking to thrive as a researcher, the School of Pharmacy offers a dynamic environment focused on impactful discoveries, making it an ideal setting to support your growth and career development.